A new model based on fuzzy integral for cancer prediction

Jinfeng Wang, Jiajie Chen, Hui Wang*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Cancer prediction models provide an important approach to assess risk and prognosis by identifying individuals and enabling estimates of the population burden and cost of cancer. Models also may aid in the evaluation of treatments and interventions. A number of statistical and machine learning techniques have been employed to develop various cancer prediction models. Meanwhile, gene selection is very important for cancer classification. We need to deal with high-dimensional gene space and few samples. But the epistasis means that some genes maybe cover or affect other genes. Fuzzy measure can describe the interaction between genes very well. In this article, we proposed one new model based on fuzzy integral with respect to fuzzy measure for cancer prediction with sparse genes. We can obtain a group of combinations of genes with the highest fuzzy measure values. The new method is applied to two cancer data for testifying the performance. Experimental results show that the proposed model has the highest testing accuracy and F-score by comparing with several state-of-the-art methods.

Original languageEnglish
Title of host publicationProceedings -2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)
EditorsHarald Schmidt, David Griol, Haiying Wang, Jan Baumbach, Huiru Zheng, Zoraida Callejas, Xiaohua Hu, Julie Dickerson, Le Zhang
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages2309-2315
Number of pages7
ISBN (Electronic)9781538654880
ISBN (Print)9781538654897
DOIs
Publication statusPublished - 24 Jan 2019
Externally publishedYes
Event2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018 - Madrid, Spain
Duration: 03 Dec 201806 Dec 2018

Publication series

NameProceedings - IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

Conference

Conference2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018
Country/TerritorySpain
CityMadrid
Period03/12/201806/12/2018

Bibliographical note

Funding Information:
This work is supported by the EU Horizon 2020 (No.: 690238), the Technology Planning Project of Guangdong Province (No.: 2017A040406023) and the Technology Planning Project of Guangzho City (No.: 201804010353). *corresponding author

Publisher Copyright:
© 2018 IEEE.

Keywords

  • Cancer prediction
  • Fuzzy measure
  • Gene selection

ASJC Scopus subject areas

  • Biomedical Engineering
  • Health Informatics

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