A nitrile-metabolising enzyme and a process for producing an acid using same

Lee Coffey; Catherine O'Reilly; Claire Lennon; Tracey Coady; Erica Owens; Panagiotis Manesiotis; Karen Tambling

A nitrile-metabolising enzyme and a process for producing an acid using same

Lee Coffey (Inventor), Catherine O'Reilly (Inventor), Claire Lennon (Inventor), Tracey Coady (Inventor), Erica Owens (Inventor), Panagiotis Manesiotis (Inventor), Karen Tambling (Inventor)

School of Chemistry and Chemical Engineering

Research output: Patent

Abstract

The present invention relates to an isolated nucleotide sequence and corresponding polypeptide derived from the nitrile-metabolising Pantoea strain deposited under NCIMB 41854. Said isolated polypeptide acts as a nitrilase and the invention extends to a process for producing a carboxylic acid using said isolated polypeptide to metabolise nitriles such as 3-hydroxyglutaronitrile, 3-hydroxybutyronitrile and 3- hydroxy-phenylpropionitrile to form corresponding carboxylic acids.

Original language	English
Patent number	WO2013004834 A1
Publication status	Published - 10 Jan 2013

Cite this

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title = "A nitrile-metabolising enzyme and a process for producing an acid using same",

abstract = "The present invention relates to an isolated nucleotide sequence and corresponding polypeptide derived from the nitrile-metabolising Pantoea strain deposited under NCIMB 41854. Said isolated polypeptide acts as a nitrilase and the invention extends to a process for producing a carboxylic acid using said isolated polypeptide to metabolise nitriles such as 3-hydroxyglutaronitrile, 3-hydroxybutyronitrile and 3- hydroxy-phenylpropionitrile to form corresponding carboxylic acids.",

author = "Lee Coffey and Catherine O'Reilly and Claire Lennon and Tracey Coady and Erica Owens and Panagiotis Manesiotis and Karen Tambling",

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T1 - A nitrile-metabolising enzyme and a process for producing an acid using same

AU - Coffey, Lee

AU - O'Reilly, Catherine

AU - Lennon, Claire

AU - Coady, Tracey

AU - Owens, Erica

AU - Manesiotis, Panagiotis

AU - Tambling, Karen

PY - 2013/1/10

Y1 - 2013/1/10

N2 - The present invention relates to an isolated nucleotide sequence and corresponding polypeptide derived from the nitrile-metabolising Pantoea strain deposited under NCIMB 41854. Said isolated polypeptide acts as a nitrilase and the invention extends to a process for producing a carboxylic acid using said isolated polypeptide to metabolise nitriles such as 3-hydroxyglutaronitrile, 3-hydroxybutyronitrile and 3- hydroxy-phenylpropionitrile to form corresponding carboxylic acids.

AB - The present invention relates to an isolated nucleotide sequence and corresponding polypeptide derived from the nitrile-metabolising Pantoea strain deposited under NCIMB 41854. Said isolated polypeptide acts as a nitrilase and the invention extends to a process for producing a carboxylic acid using said isolated polypeptide to metabolise nitriles such as 3-hydroxyglutaronitrile, 3-hydroxybutyronitrile and 3- hydroxy-phenylpropionitrile to form corresponding carboxylic acids.

M3 - Patent

M1 - WO2013004834 A1

ER -

A nitrile-metabolising enzyme and a process for producing an acid using same

Abstract

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