A nitrile-metabolising enzyme and a process for producing an acid using same

Lee Coffey; Catherine O'Reilly; Claire Lennon; Tracey Coady; Erica Owens; Panagiotis Manesiotis; Karen Tambling

A nitrile-metabolising enzyme and a process for producing an acid using same

Lee Coffey (Inventor)
, Catherine O'Reilly (Inventor)
, Claire Lennon (Inventor)
, Tracey Coady (Inventor)
, Erica Owens (Inventor)
, Panagiotis Manesiotis (Inventor)
, Karen Tambling (Inventor)

School of Chemistry and Chemical Engineering

Research output: Patent

Abstract

The present invention relates to an isolated nucleotide sequence and corresponding polypeptide derived from the nitrile-metabolising Pantoea strain deposited under NCIMB 41854. Said isolated polypeptide acts as a nitrilase and the invention extends to a process for producing a carboxylic acid using said isolated polypeptide to metabolise nitriles such as 3-hydroxyglutaronitrile, 3-hydroxybutyronitrile and 3- hydroxy-phenylpropionitrile to form corresponding carboxylic acids.

Original language	English
Patent number	WO2013004834 A1
Publication status	Published - 10 Jan 2013

Cite this

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title = "A nitrile-metabolising enzyme and a process for producing an acid using same",

abstract = "The present invention relates to an isolated nucleotide sequence and corresponding polypeptide derived from the nitrile-metabolising Pantoea strain deposited under NCIMB 41854. Said isolated polypeptide acts as a nitrilase and the invention extends to a process for producing a carboxylic acid using said isolated polypeptide to metabolise nitriles such as 3-hydroxyglutaronitrile, 3-hydroxybutyronitrile and 3- hydroxy-phenylpropionitrile to form corresponding carboxylic acids.",

author = "Lee Coffey and Catherine O'Reilly and Claire Lennon and Tracey Coady and Erica Owens and Panagiotis Manesiotis and Karen Tambling",

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T1 - A nitrile-metabolising enzyme and a process for producing an acid using same

AU - Coffey, Lee

AU - O'Reilly, Catherine

AU - Lennon, Claire

AU - Coady, Tracey

AU - Owens, Erica

AU - Manesiotis, Panagiotis

AU - Tambling, Karen

PY - 2013/1/10

Y1 - 2013/1/10

N2 - The present invention relates to an isolated nucleotide sequence and corresponding polypeptide derived from the nitrile-metabolising Pantoea strain deposited under NCIMB 41854. Said isolated polypeptide acts as a nitrilase and the invention extends to a process for producing a carboxylic acid using said isolated polypeptide to metabolise nitriles such as 3-hydroxyglutaronitrile, 3-hydroxybutyronitrile and 3- hydroxy-phenylpropionitrile to form corresponding carboxylic acids.

AB - The present invention relates to an isolated nucleotide sequence and corresponding polypeptide derived from the nitrile-metabolising Pantoea strain deposited under NCIMB 41854. Said isolated polypeptide acts as a nitrilase and the invention extends to a process for producing a carboxylic acid using said isolated polypeptide to metabolise nitriles such as 3-hydroxyglutaronitrile, 3-hydroxybutyronitrile and 3- hydroxy-phenylpropionitrile to form corresponding carboxylic acids.

M3 - Patent

M1 - WO2013004834 A1

ER -

A nitrile-metabolising enzyme and a process for producing an acid using same

Abstract

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Cite this