A Non-Inferiority Randomized Controlled Trial Comparing the Clinical Effectiveness of Anesthesia Obtained by Application of a Novel Topical Anesthetic Putty With the Infiltration of Lidocaine for the Treatment of Lacerations in the Emergency Department

Mark G Jenkins; Diarmaid J Murphy; Carol Little; Julie McDonald; Paul A McCarron

doi:10.1016/j.annemergmed.2013.12.012

A Non-Inferiority Randomized Controlled Trial Comparing the Clinical Effectiveness of Anesthesia Obtained by Application of a Novel Topical Anesthetic Putty With the Infiltration of Lidocaine for the Treatment of Lacerations in the Emergency Department

Mark G Jenkins
, Diarmaid J Murphy
, Carol Little
, Julie McDonald
, Paul A McCarron

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

We test the hypothesis that anesthesia, measured as pain scores, induced by a novel topical anesthetic putty is non-inferior (margin=1.3) to that provided by conventional lidocaine infiltration for the repair of lacerations.

Original language	English
Pages (from-to)	704-710
Number of pages	7
Journal	Annals of emergency medicine
Volume	63
Issue number	6
DOIs	https://doi.org/10.1016/j.annemergmed.2013.12.012
Publication status	Published - Jun 2014

Keywords

Adolescent
Adult
Aged
Aged, 80 and over
Anesthetics, Local
Female
Humans
Lacerations
Lidocaine
Male
Middle Aged
Pain Management
Pain Measurement
Treatment Outcome
Wound Healing
Young Adult

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10.1016/j.annemergmed.2013.12.012

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Jenkins, M. G., Murphy, D. J., Little, C., McDonald, J., & McCarron, P. A. (2014). A Non-Inferiority Randomized Controlled Trial Comparing the Clinical Effectiveness of Anesthesia Obtained by Application of a Novel Topical Anesthetic Putty With the Infiltration of Lidocaine for the Treatment of Lacerations in the Emergency Department. Annals of emergency medicine, 63(6), 704-710. https://doi.org/10.1016/j.annemergmed.2013.12.012

Jenkins, Mark G ; Murphy, Diarmaid J ; Little, Carol et al. / A Non-Inferiority Randomized Controlled Trial Comparing the Clinical Effectiveness of Anesthesia Obtained by Application of a Novel Topical Anesthetic Putty With the Infiltration of Lidocaine for the Treatment of Lacerations in the Emergency Department. In: Annals of emergency medicine. 2014 ; Vol. 63, No. 6. pp. 704-710.

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title = "A Non-Inferiority Randomized Controlled Trial Comparing the Clinical Effectiveness of Anesthesia Obtained by Application of a Novel Topical Anesthetic Putty With the Infiltration of Lidocaine for the Treatment of Lacerations in the Emergency Department",

abstract = "We test the hypothesis that anesthesia, measured as pain scores, induced by a novel topical anesthetic putty is non-inferior (margin=1.3) to that provided by conventional lidocaine infiltration for the repair of lacerations.",

keywords = "Adolescent, Adult, Aged, Aged, 80 and over, Anesthetics, Local, Female, Humans, Lacerations, Lidocaine, Male, Middle Aged, Pain Management, Pain Measurement, Treatment Outcome, Wound Healing, Young Adult",

author = "Jenkins, \{Mark G\} and Murphy, \{Diarmaid J\} and Carol Little and Julie McDonald and McCarron, \{Paul A\}",

year = "2014",

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doi = "10.1016/j.annemergmed.2013.12.012",

language = "English",

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Jenkins, MG, Murphy, DJ, Little, C, McDonald, J & McCarron, PA 2014, 'A Non-Inferiority Randomized Controlled Trial Comparing the Clinical Effectiveness of Anesthesia Obtained by Application of a Novel Topical Anesthetic Putty With the Infiltration of Lidocaine for the Treatment of Lacerations in the Emergency Department', Annals of emergency medicine, vol. 63, no. 6, pp. 704-710. https://doi.org/10.1016/j.annemergmed.2013.12.012

A Non-Inferiority Randomized Controlled Trial Comparing the Clinical Effectiveness of Anesthesia Obtained by Application of a Novel Topical Anesthetic Putty With the Infiltration of Lidocaine for the Treatment of Lacerations in the Emergency Department. / Jenkins, Mark G; Murphy, Diarmaid J; Little, Carol et al.
In: Annals of emergency medicine, Vol. 63, No. 6, 06.2014, p. 704-710.

Research output: Contribution to journal › Article › peer-review

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KW - Aged

KW - Aged, 80 and over

KW - Anesthetics, Local

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KW - Humans

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KW - Male

KW - Middle Aged

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KW - Treatment Outcome

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Jenkins MG, Murphy DJ, Little C, McDonald J, McCarron PA. A Non-Inferiority Randomized Controlled Trial Comparing the Clinical Effectiveness of Anesthesia Obtained by Application of a Novel Topical Anesthetic Putty With the Infiltration of Lidocaine for the Treatment of Lacerations in the Emergency Department. Annals of emergency medicine. 2014 Jun;63(6):704-710. doi: 10.1016/j.annemergmed.2013.12.012