A study of three cases of familial related agenesis of the corpus callosum

D C Finlay, T Peto, J Payling, M Hunter, W R Fulham, I Wilkinson

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15 Citations (Scopus)


This paper provides data on a family in which three members, all female, have been diagnosed as having agenesis of the corpus callosum. That all three acallosal individuals came from the same family and showed relatively uniform neuropsychological impairment and could be compared in similar terms with their "callosal" siblings, also female, provides a unique sample. Inter-hemispheric transfer, psychometric measures, and motor and cognitive function were examined in the acallosal individuals, all of whom had borderline to low-average intelligence, with results compared to their non-acallosal siblings. The data indicated that all acallosal individuals exhibited deficits with the cognitive tests indicating difficulties of inter-hemispheric transfer of tactile information, difficulties in some areas of memory and, at least as far as the children are concerned, a marked difference in Verbal IQ and Performance IQ.

Original languageEnglish
Pages (from-to)731-42
Number of pages12
JournalJournal of clinical and experimental neuropsychology
Issue number6
Publication statusPublished - Dec 2000


  • Adolescent
  • Adult
  • Agenesis of Corpus Callosum
  • Brain Diseases
  • Child
  • Corpus Callosum
  • Female
  • Functional Laterality
  • Humans
  • Intelligence
  • Learning
  • Neuropsychological Tests
  • Psychometrics
  • Psychomotor Performance
  • Reading
  • Case Reports
  • Journal Article
  • Research Support, Non-U.S. Gov't


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