A Synthesis of (S)-(-)-Umbelactone and Related α,β-Butenolides

William Goldring, John Mann, Paul Brockbank

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


The development of an asymmetric route for the synthesis of alpha,beta-butenolide building blocks, starting from commercially available D-mannitol, is described. The devised route was applied to a synthesis of the (S)-(–)-enantiomer of the antiviral natural product umbelactone, together with the construction of other synthetically useful lactone structures.
Original languageEnglish
Article numberD29309ST
Pages (from-to)547-550
Number of pages4
Issue number4
Publication statusPublished - Mar 2010

ASJC Scopus subject areas

  • Organic Chemistry


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