Abstract
The development of an asymmetric route for the synthesis
of alpha,beta-butenolide building blocks, starting from commercially available D-mannitol, is described. The devised route was applied to a synthesis of the (S)-(–)-enantiomer of the antiviral natural product umbelactone, together with the construction of other synthetically useful lactone structures.
Original language | English |
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Article number | D29309ST |
Pages (from-to) | 547-550 |
Number of pages | 4 |
Journal | Synlett |
Volume | 2010 |
Issue number | 4 |
DOIs | |
Publication status | Published - Mar 2010 |
ASJC Scopus subject areas
- Organic Chemistry