A zipper-like on/off-switchable molecularly imprinted polymer

Songjun Li*, Yi Ge, Sergey A. Piletsky, Anthony P F Turner

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

49 Citations (Scopus)

Abstract

A zipper-like on/off-switchable molecularly imprinted polymer is reported. This unique imprinted polymer was composed of template-imprinted polymeric networks that incorporate zipper-like interactions between poly(acrylamide) (PAAm) and poly(2-acrylamide-2-methyl propanesulfonic acid) (PAMPS). This polymer showed marginal recognition ability towards the imprint species under low temperature conditions, due to the interpolymer interaction between PAAm and PAMPS, which inhibited access to the imprinted networks. In contrast, at relatively high temperatures (such as 40 °C), the polymer demonstrated significant molecular recognition ability towards the imprint species resulting from the dissociation of the interpolymer complexes of PAAm and PAMPS, which enabled access to the imprint networks. Unlike previously reported PNIPAm-based imprinted polymers, which demonstrate alterable molecular recognition simply because of the thermosensitive hydrophilicity/hydrophobicity of PNIPAm, this polymer employed a zipper-like supramolecular architecture between PAAm and PAMPS, thereby enabling switchable molecular recognition. A zipper-like on/off-switchable molecularly imprinted polymer is reported. This unique imprinted polymer was composed of template-imprinted polymeric networks that incorporate zipper-like interactions between PAAm and PAMPS. The complexation and dissociation between PAAm and PAMPS regulated the access of analyte to the imprinted networks, thereby enabling on/off-switchable molecular recognition.

Original languageEnglish
Pages (from-to)3344-3349
Number of pages6
JournalAdvanced Functional Materials
Volume21
Issue number17
DOIs
Publication statusPublished - 09 Sep 2011
Externally publishedYes

Keywords

  • host-guest interaction
  • modulation
  • molecular recognition
  • molecularly imprinted polymers

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Condensed Matter Physics
  • Electrochemistry

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