Absence of evidence of porcine circovirus infection in piglets with congenital tremors

Seamus Kennedy*, Joaquim Segalés, Albert Rovira, Sandra Scholes, Mariano Domingo, Deborah Moffett, Brian Meehan, Ronan O'Neill, Francis McNeilly, Gordon Allan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)


Porcine circovirus types 1 (PCV1) and 2 (PCV2) have been associated with congenital tremors (CTs) in piglets in the United States. In this study, central nervous system and nonneural tissues of 40 CT piglets from Spain, the United Kingdom, Ireland, and Sweden were investigated for the presence of PCVl and PCV2 using in situ hybridization and immunohistochemical labeling on paraffin sections. The polymerase chain reaction for PCV2 was also carried out on sera from the Spanish CT cases. No evidence of circovirus nucleic acid or antigen was found in any CT piglet. Although these results do not support the hypothesis that PCVl or PCV2 are linked to porcine CT, they cannot disprove it.

Original languageEnglish
Pages (from-to)151-156
Number of pages6
JournalJournal of Veterinary Diagnostic Investigation
Issue number2
Publication statusPublished - Mar 2003
Externally publishedYes

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ASJC Scopus subject areas

  • veterinary(all)


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