Acid-mediated topological control in a functionalized foldamer

Peter C. Knipe, Sam Thompson*, Andrew D. Hamilton

*Corresponding author for this work

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Induced conformational change provides a powerful mechanism to modulate the structure and function of molecules. Here we describe the synthesis of chiral, surface-functionalized oligomeric pyridine/imidazolidin-2-one foldamers, and interrogate their acid-mediated transition between linear and helical topologies.

Original languageEnglish
Pages (from-to)6521-6524
Number of pages4
JournalChemical Communications
Volume52
Issue number39
Early online date21 Mar 2016
DOIs
Publication statusPublished - 2016

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Keywords

  • foldamer
  • switching
  • oligomer
  • acid
  • conformation
  • supramolecular
  • helix

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