Abstract
Induced conformational change provides a powerful mechanism to modulate the structure and function of molecules. Here we describe the synthesis of chiral, surface-functionalized oligomeric pyridine/imidazolidin-2-one foldamers, and interrogate their acid-mediated transition between linear and helical topologies.
| Original language | English |
|---|---|
| Pages (from-to) | 6521-6524 |
| Number of pages | 4 |
| Journal | Chemical Communications |
| Volume | 52 |
| Issue number | 39 |
| Early online date | 21 Mar 2016 |
| DOIs | |
| Publication status | Published - 2016 |
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Keywords
- foldamer
- switching
- oligomer
- acid
- conformation
- supramolecular
- helix
Cite this
Knipe, P. C., Thompson, S., & Hamilton, A. D. (2016). Acid-mediated topological control in a functionalized foldamer. Chemical Communications, 52(39), 6521-6524. https://doi.org/10.1039/c6cc01496h