Acid-mediated topological control in a functionalized foldamer

Peter C. Knipe, Sam Thompson*, Andrew D. Hamilton

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


Induced conformational change provides a powerful mechanism to modulate the structure and function of molecules. Here we describe the synthesis of chiral, surface-functionalized oligomeric pyridine/imidazolidin-2-one foldamers, and interrogate their acid-mediated transition between linear and helical topologies.

Original languageEnglish
Pages (from-to)6521-6524
Number of pages4
JournalChemical Communications
Issue number39
Early online date21 Mar 2016
Publication statusPublished - 2016


  • foldamer
  • switching
  • oligomer
  • acid
  • conformation
  • supramolecular
  • helix

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Ceramics and Composites
  • Electronic, Optical and Magnetic Materials
  • Surfaces, Coatings and Films
  • Materials Chemistry
  • Metals and Alloys


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