Acid-mediated topological control in a functionalized foldamer

Peter C. Knipe, Sam Thompson, Andrew D. Hamilton

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Induced conformational change provides a powerful mechanism to modulate the structure and function of molecules. Here we describe the synthesis of chiral, surface-functionalized oligomeric pyridine/imidazolidin-2-one foldamers, and interrogate their acid-mediated transition between linear and helical topologies.

LanguageEnglish
Pages6521-6524
Number of pages4
JournalChemical Communications
Volume52
Issue number39
Early online date21 Mar 2016
DOIs
Publication statusPublished - 2016

Fingerprint

Pyridine
Topology
Molecules
Acids
pyridine
ethylene urea

Keywords

  • foldamer
  • switching
  • oligomer
  • acid
  • conformation
  • supramolecular
  • helix

Cite this

Knipe, Peter C. ; Thompson, Sam ; Hamilton, Andrew D. / Acid-mediated topological control in a functionalized foldamer. In: Chemical Communications. 2016 ; Vol. 52, No. 39. pp. 6521-6524.
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Acid-mediated topological control in a functionalized foldamer. / Knipe, Peter C.; Thompson, Sam; Hamilton, Andrew D.

In: Chemical Communications, Vol. 52, No. 39, 2016, p. 6521-6524.

Research output: Contribution to journalArticle

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