Actin-binding proteins in the Arabidopsis genome database: properties of functionally distinct plant actin-depolymerizing factors/cofilins

PJ Hussey*, EG Allwood, AP Smertenko

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

63 Citations (Scopus)

Abstract

The plant actin cytoskeleton is a highly dynamic, fibrous structure essential in many cellular processes including cell division and cytoplasmic streaming. This structure is stimulus responsive, being affected by internal stimuli, by biotic and abiotic stresses mediated in signal transduction pathways by actin-binding proteins. The completion of the Arabidopsis genome sequence has allowed a comparative identification of many actin-binding proteins. However, not all are conserved in plants, which possibly reflects the differences in the processes involved in morphogenesis between plant and other cells. Here we have searched for the Arabidopsis equivalents of 67 animal/fungal actin-binding proteins and show that 36 are not conserved in plants. One protein that is conserved across phylogeny is actin-depolymerizing factor or cofilin and we describe our work on the activity of vegetative tissue and pollen-specific isoforms of this protein in plant cells, concluding that they are functionally distinct.

Original languageEnglish
Pages (from-to)791-798
Number of pages8
JournalPhilosophical Transactions of the Royal Society of London B: Biological Sciences
Volume357
Issue number1422
DOIs
Publication statusPublished - 29 Jun 2002
EventDiscussion Meeting on Plant Cell - Between Genome and Plant - LONDON, United Kingdom
Duration: 13 Jun 200114 Jun 2001

Keywords

  • actin-binding proteins
  • F-ACTIN
  • actin-depolymerizing factor
  • COFILIN
  • Arabidopsis genome
  • PHOSPHORYLATION
  • DYNAMICS
  • SEVERING PROTEIN
  • cofilin
  • IN-VIVO
  • POLLEN
  • root hairs
  • ADF/COFILIN FAMILY
  • pollen tubes
  • KINASE
  • FILAMENT TURNOVER

Fingerprint

Dive into the research topics of 'Actin-binding proteins in the Arabidopsis genome database: properties of functionally distinct plant actin-depolymerizing factors/cofilins'. Together they form a unique fingerprint.

Cite this