Acute skin GVHD following syngeneic BMT for CLL

M Deane; C Singer; M Lawler; S McElwaine; K Gomez; H G Prentice; Mark Lawler

doi:10.1038/sj.bmt.1701515

Acute skin GVHD following syngeneic BMT for CLL

M Deane, C Singer, M Lawler, S McElwaine, K Gomez, H G Prentice, Mark Lawler

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

A 41-year-old woman received a syngeneic BMT for CLL and subsequently developed acute skin GVHD. Transfusion-related allogeneic GVHD was excluded on the basis of an unchanged HLA type in circulating lymphocytes. Short tandem repeat PCR was used to confirm syngeneicity between donor and recipient. The patient had a personal and family history of autoimmune disease which may have made her particularly susceptible to development of syngeneic GVHD. The distinction between allogeneic and syngeneic or autologous GVHD is important because of therapeutic implications.

Original language	English
Pages (from-to)	1207-9
Number of pages	3
Journal	Bone Marrow Transplantation
Volume	22
Issue number	12
DOIs	https://doi.org/10.1038/sj.bmt.1701515
Publication status	Published - Dec 1998

Keywords

Acute Disease
Adult
Bone Marrow
Bone Marrow Transplantation
Female
Graft vs Host Disease
Humans
Leukemia, Lymphocytic, Chronic, B-Cell
Skin Diseases
Transplantation Chimera
Transplantation, Isogeneic

Access to Document

10.1038/sj.bmt.1701515

Cite this

@article{971a797ac48749aa97a2cad4fd4248fe,

title = "Acute skin GVHD following syngeneic BMT for CLL",

abstract = "A 41-year-old woman received a syngeneic BMT for CLL and subsequently developed acute skin GVHD. Transfusion-related allogeneic GVHD was excluded on the basis of an unchanged HLA type in circulating lymphocytes. Short tandem repeat PCR was used to confirm syngeneicity between donor and recipient. The patient had a personal and family history of autoimmune disease which may have made her particularly susceptible to development of syngeneic GVHD. The distinction between allogeneic and syngeneic or autologous GVHD is important because of therapeutic implications.",

keywords = "Acute Disease, Adult, Bone Marrow, Bone Marrow Transplantation, Female, Graft vs Host Disease, Humans, Leukemia, Lymphocytic, Chronic, B-Cell, Skin Diseases, Transplantation Chimera, Transplantation, Isogeneic",

author = "M Deane and C Singer and M Lawler and S McElwaine and K Gomez and Prentice, {H G} and Mark Lawler",

year = "1998",

month = dec,

doi = "10.1038/sj.bmt.1701515",

language = "English",

volume = "22",

pages = "1207--9",

journal = "Bone Marrow Transplantation",

issn = "0268-3369",

publisher = "Nature Publishing Group",

number = "12",

}

TY - JOUR

T1 - Acute skin GVHD following syngeneic BMT for CLL

AU - Deane, M

AU - Singer, C

AU - Lawler, M

AU - McElwaine, S

AU - Gomez, K

AU - Prentice, H G

AU - Lawler, Mark

PY - 1998/12

Y1 - 1998/12

N2 - A 41-year-old woman received a syngeneic BMT for CLL and subsequently developed acute skin GVHD. Transfusion-related allogeneic GVHD was excluded on the basis of an unchanged HLA type in circulating lymphocytes. Short tandem repeat PCR was used to confirm syngeneicity between donor and recipient. The patient had a personal and family history of autoimmune disease which may have made her particularly susceptible to development of syngeneic GVHD. The distinction between allogeneic and syngeneic or autologous GVHD is important because of therapeutic implications.

AB - A 41-year-old woman received a syngeneic BMT for CLL and subsequently developed acute skin GVHD. Transfusion-related allogeneic GVHD was excluded on the basis of an unchanged HLA type in circulating lymphocytes. Short tandem repeat PCR was used to confirm syngeneicity between donor and recipient. The patient had a personal and family history of autoimmune disease which may have made her particularly susceptible to development of syngeneic GVHD. The distinction between allogeneic and syngeneic or autologous GVHD is important because of therapeutic implications.

KW - Acute Disease

KW - Adult

KW - Bone Marrow

KW - Bone Marrow Transplantation

KW - Female

KW - Graft vs Host Disease

KW - Humans

KW - Leukemia, Lymphocytic, Chronic, B-Cell

KW - Skin Diseases

KW - Transplantation Chimera

KW - Transplantation, Isogeneic

U2 - 10.1038/sj.bmt.1701515

DO - 10.1038/sj.bmt.1701515

M3 - Article

C2 - 9894725

VL - 22

SP - 1207

EP - 1209

JO - Bone Marrow Transplantation

JF - Bone Marrow Transplantation

SN - 0268-3369

IS - 12

ER -

Acute skin GVHD following syngeneic BMT for CLL

Abstract

Keywords

Access to Document

Fingerprint

Cite this