Advanced glycation end-products and methionine sulphoxide in skin collagen of patients with type 1 diabetes

Y Yu; S R Thorpe; A J Jenkins; J N Shaw; M A Sochaski; D McGee; C E Aston; T J Orchard; N Silvers; Y G Peng; J A McKnight; J W Baynes; T J Lyons; DCCT/EDIC Research Group

doi:10.1007/s00125-006-0355-8

Advanced glycation end-products and methionine sulphoxide in skin collagen of patients with type 1 diabetes

Y Yu, S R Thorpe, A J Jenkins, J N Shaw, M A Sochaski, D McGee, C E Aston, T J Orchard, N Silvers, Y G Peng, J A McKnight, J W Baynes, T J Lyons, DCCT/EDIC Research Group

School of Medicine, Dentistry and Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

57 Citations (Scopus)

Abstract

We determined whether oxidative damage in collagen is increased in (1) patients with diabetes; (2) patients with diabetic complications; and (3) subjects from the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) study, with comparison of subjects from the former standard vs intensive treatment groups 4 years after DCCT completion.

Original language	English
Pages (from-to)	2488-98
Number of pages	11
Journal	Diabetologia
Volume	49
Issue number	10
DOIs	https://doi.org/10.1007/s00125-006-0355-8
Publication status	Published - Oct 2006

Keywords

Adult
Aged
Biopsy
Cholesterol, HDL
Cholesterol, LDL
Collagen
Diabetes Mellitus, Type 1
Female
Glycosylation End Products, Advanced
Hemoglobin A, Glycosylated
Humans
Male
Methionine
Middle Aged
Reference Values
Skin
Triglycerides

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s00125-006-0355-8

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Yu, Y., Thorpe, S. R., Jenkins, A. J., Shaw, J. N., Sochaski, M. A., McGee, D., Aston, C. E., Orchard, T. J., Silvers, N., Peng, Y. G., McKnight, J. A., Baynes, J. W., Lyons, T. J., & DCCT/EDIC Research Group (2006). Advanced glycation end-products and methionine sulphoxide in skin collagen of patients with type 1 diabetes. Diabetologia, 49(10), 2488-98. https://doi.org/10.1007/s00125-006-0355-8

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title = "Advanced glycation end-products and methionine sulphoxide in skin collagen of patients with type 1 diabetes",

abstract = "We determined whether oxidative damage in collagen is increased in (1) patients with diabetes; (2) patients with diabetic complications; and (3) subjects from the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) study, with comparison of subjects from the former standard vs intensive treatment groups 4 years after DCCT completion.",

keywords = "Adult, Aged, Biopsy, Cholesterol, HDL, Cholesterol, LDL, Collagen, Diabetes Mellitus, Type 1, Female, Glycosylation End Products, Advanced, Hemoglobin A, Glycosylated, Humans, Male, Methionine, Middle Aged, Reference Values, Skin, Triglycerides",

author = "Y Yu and Thorpe, {S R} and Jenkins, {A J} and Shaw, {J N} and Sochaski, {M A} and D McGee and Aston, {C E} and Orchard, {T J} and N Silvers and Peng, {Y G} and McKnight, {J A} and Baynes, {J W} and Lyons, {T J} and {DCCT/EDIC Research Group}",

year = "2006",

month = oct,

doi = "10.1007/s00125-006-0355-8",

language = "English",

volume = "49",

pages = "2488--98",

journal = "Diabetologia",

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publisher = "Springer Science and Business Media Deutschland GmbH",

number = "10",

}

Yu, Y, Thorpe, SR, Jenkins, AJ, Shaw, JN, Sochaski, MA, McGee, D, Aston, CE, Orchard, TJ, Silvers, N, Peng, YG, McKnight, JA, Baynes, JW, Lyons, TJ & DCCT/EDIC Research Group 2006, 'Advanced glycation end-products and methionine sulphoxide in skin collagen of patients with type 1 diabetes', Diabetologia, vol. 49, no. 10, pp. 2488-98. https://doi.org/10.1007/s00125-006-0355-8

TY - JOUR

T1 - Advanced glycation end-products and methionine sulphoxide in skin collagen of patients with type 1 diabetes

AU - Yu, Y

AU - Thorpe, S R

AU - Jenkins, A J

AU - Shaw, J N

AU - Sochaski, M A

AU - McGee, D

AU - Aston, C E

AU - Orchard, T J

AU - Silvers, N

AU - Peng, Y G

AU - McKnight, J A

AU - Baynes, J W

AU - Lyons, T J

AU - DCCT/EDIC Research Group

PY - 2006/10

Y1 - 2006/10

N2 - We determined whether oxidative damage in collagen is increased in (1) patients with diabetes; (2) patients with diabetic complications; and (3) subjects from the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) study, with comparison of subjects from the former standard vs intensive treatment groups 4 years after DCCT completion.

AB - We determined whether oxidative damage in collagen is increased in (1) patients with diabetes; (2) patients with diabetic complications; and (3) subjects from the Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) study, with comparison of subjects from the former standard vs intensive treatment groups 4 years after DCCT completion.

KW - Adult

KW - Aged

KW - Biopsy

KW - Cholesterol, HDL

KW - Cholesterol, LDL

KW - Collagen

KW - Diabetes Mellitus, Type 1

KW - Female

KW - Glycosylation End Products, Advanced

KW - Hemoglobin A, Glycosylated

KW - Humans

KW - Male

KW - Methionine

KW - Middle Aged

KW - Reference Values

KW - Skin

KW - Triglycerides

U2 - 10.1007/s00125-006-0355-8

DO - 10.1007/s00125-006-0355-8

M3 - Article

C2 - 16955213

SN - 0012-186X

VL - 49

SP - 2488

EP - 2498

JO - Diabetologia

JF - Diabetologia

IS - 10

ER -

Advanced glycation end-products and methionine sulphoxide in skin collagen of patients with type 1 diabetes

Abstract

Keywords

UN SDGs

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