Alternative Factor Models and Heritability of the Short Leyton Obsessional Inventory-Children's Version

Janette Moore, Gillian W. Smith, Mark Shevlin, Francis A. O'Neill

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

An alternative models framework was used to test three confirmatory factor analytic models for the Short Leyton Obsessional Inventory-Children's Version (Short LOI-CV) in a general population sample of 517 young adolescent twins (11-16 years). A one-factor model as implicit in current classification systems of Obsessive-Compulsive Disorder (OCD), a two-factor obsessions and compulsions model, and a multidimensional model corresponding to the three proposed subscales of the Short LOI-CV (labelled Obsessions/Incompleteness, Numbers/Luck and Cleanliness) were considered. The three-factor model was the only model to provide an adequate explanation of the data. Twin analyses suggested significant quantitative sex differences in heritability for both the Obsessions/Incompleteness and Numbers/Luck dimensions with these being significantly heritable in males only (heritability of 60% and 65% respectively). The correlation between the additive genetic effects for these two dimensions in males was 0.95 suggesting they largely share the same genetic risk factors.
Original languageEnglish
Pages (from-to)921-934
Number of pages14
JournalJournal of Abnormal Child Psychology
Volume38
Issue number7
DOIs
Publication statusPublished - Oct 2010

ASJC Scopus subject areas

  • Developmental and Educational Psychology
  • Psychiatry and Mental health

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