Aminolevulinic acid-loaded Witepsol microparticles manufactured using a spray congealing procedure: implications for topical photodynamic therapy

R. Al-Kassas; Ryan Donnelly; Paul McCarron

doi:10.1211/jpp/61.09.0001

Aminolevulinic acid-loaded Witepsol microparticles manufactured using a spray congealing procedure: implications for topical photodynamic therapy

R. Al-Kassas, Ryan Donnelly, Paul McCarron

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Objectives The aim was to enhance aminolevulinic acid (ALA) stability by incorporation into low-melting microparticles prepared using a spray congealing procedure and to evaluate temperature-triggered release, allowing topical bioavailability following melting at skin temperature.

Original language	English
Pages (from-to)	1125-1135
Number of pages	11
Journal	Journal of Pharmacy and Pharmacology
Volume	61
Issue number	9
DOIs	https://doi.org/10.1211/jpp/61.09.0001
Publication status	Published - 2009

ASJC Scopus subject areas

Pharmaceutical Science
Pharmacology

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title = "Aminolevulinic acid-loaded Witepsol microparticles manufactured using a spray congealing procedure: implications for topical photodynamic therapy",

abstract = "Objectives The aim was to enhance aminolevulinic acid (ALA) stability by incorporation into low-melting microparticles prepared using a spray congealing procedure and to evaluate temperature-triggered release, allowing topical bioavailability following melting at skin temperature.",

author = "R. Al-Kassas and Ryan Donnelly and Paul McCarron",

year = "2009",

doi = "10.1211/jpp/61.09.0001",

language = "English",

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pages = "1125--1135",

journal = "Journal of Pharmacy and Pharmacology",

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T1 - Aminolevulinic acid-loaded Witepsol microparticles manufactured using a spray congealing procedure: implications for topical photodynamic therapy

AU - Al-Kassas, R.

AU - Donnelly, Ryan

AU - McCarron, Paul

PY - 2009

Y1 - 2009

N2 - Objectives The aim was to enhance aminolevulinic acid (ALA) stability by incorporation into low-melting microparticles prepared using a spray congealing procedure and to evaluate temperature-triggered release, allowing topical bioavailability following melting at skin temperature.

AB - Objectives The aim was to enhance aminolevulinic acid (ALA) stability by incorporation into low-melting microparticles prepared using a spray congealing procedure and to evaluate temperature-triggered release, allowing topical bioavailability following melting at skin temperature.

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U2 - 10.1211/jpp/61.09.0001

DO - 10.1211/jpp/61.09.0001

M3 - Article

VL - 61

SP - 1125

EP - 1135

JO - Journal of Pharmacy and Pharmacology

JF - Journal of Pharmacy and Pharmacology

SN - 0022-3573

IS - 9

ER -

Aminolevulinic acid-loaded Witepsol microparticles manufactured using a spray congealing procedure: implications for topical photodynamic therapy

Abstract

ASJC Scopus subject areas

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