An evaluation of protocolised weaning on the duration of mechanical ventilation

Bronagh Blackwood, J. Wilson-Barmett, Christopher Patterson, T.J. Trinder, G.G. Lavery

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26 Citations (Scopus)
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Using a before and after study design, we compared protocolised weaning from mechanical ventilation with usual non-protocolised practice in intensive care. Outcomes (duration of mechanical ventilation, duration of intubation, intensive care stay) and complications (re-intubations, tracheostomy, mortality) were compared between baseline (Phase I) and following implementation of protocolised weaning (Phase II). Over the same period, we collected data in a second (reference) unit to monitor practice changes over time. In the intervention unit, outcomes were longer in Phase II compared with Phase I (all p < 0.005). When adjusted for admission APACHE II score and diagnostic category, only intensive care stay remained significantly longer (p = 0.002). There were significantly more tracheostomies in Phase II (p = 0.004). The reference unit demonstrated no statistically significant differences in study outcomes or complications between Phases. Protocolised weaning did not reduce the duration of mechanical ventilation and was not associated with an increased rate of re-intubation or intensive care unit mortality.
Original languageEnglish
Pages (from-to)1079-1086
Number of pages8
Issue number11
Early online date16 Oct 2006
Publication statusPublished - Nov 2006

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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