An experimental study of quinine blindness

T. A. Buchanan, R. W. Lyness, A. D. Collins, T. A. Gardiner, D. B. Archer

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


An experimental model of quinine induced blindness is presented. Electrophysiological, angiographical and morphological examinations were made. The occurrence of blindness and any recovery from blindness was dependent upon the dose of quinine taken. As no evidence of acute retinal ischaemia was found it is concluded that quinine is retinotoxic.
Original languageUndefined/Unknown
Pages (from-to)522-524
Number of pages3
Volume1 ( Pt 4)
Issue numberPt 4
Publication statusPublished - 1987

Bibliographical note

LR: 20091103; JID: 8703986; 130-95-0 (Quinine); ppublish


  • Animals
  • Blindness/chemically induced/physiopathology
  • Cats
  • Disease Models, Animal
  • Dose-Response Relationship, Drug
  • Electroretinography
  • Evoked Potentials, Visual
  • Female
  • Male
  • Microscopy, Electron
  • Quinine/toxicity
  • Retina/drug effects/ultrastructure
  • Retinal Diseases/pathology

Cite this