An overview of the Feedstuffs-RADIUS project: Rapid detection of banned antibiotics in animal feeds

C. T. Elliott*, C. Situ, C. van Poucke

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The use of antimicrobial compounds as growth promoting substances has been a contentious issue for several years. Some believe that this widespread use of antibacterial substances worldwide is a significant contributor to the growing problem of bacterial antibiotic resistance that is having major adverse implications for human health. For this reason the European Commission took the decision to ban a number of antimicrobial compounds for use as growth promoting agents, i.e. zinc-bacitracin, spiramycin, tylosin, virginiamycin and olaquindox. However, in order to enforce this ban a new generation of reliable and sensitive analytical tests were required which could detect the presence of these drugs at low levels (i.e. at 20% of previously authorised minimum concentrations) in animal feeds. Based on this fact the Commission funded two research projects aimed at delivering the required methods. One of these projects, Feedstuffs-RADIUS, has recently ended. This project has been highly successful in delivering very high quality screening and confirmatory procedures capable of detecting five of the major antimicrobial growth promoters that were used in agricultural practise. The screening procedure is based on ELISA and the confirmatory technique utilises LC-MS/MS, and both were subjected to collaborative studies.

Original languageEnglish
Title of host publicationAntimicrobial Growth Promoters
Subtitle of host publicationWhere do we go from here?
PublisherWageningen Academic Publishers
Pages195-210
Number of pages16
ISBN (Print)9789076998879
DOIs
Publication statusPublished - 01 Dec 2006

Keywords

  • Antimicrobial growth promoters
  • Ban
  • Confirmation
  • Control
  • Screening

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Engineering(all)

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  • Cite this

    Elliott, C. T., Situ, C., & van Poucke, C. (2006). An overview of the Feedstuffs-RADIUS project: Rapid detection of banned antibiotics in animal feeds. In Antimicrobial Growth Promoters: Where do we go from here? (pp. 195-210). Wageningen Academic Publishers. https://doi.org/10.3920/978-90-8686-570-3