Abstract
An iris tumor developed in a 37-year-old woman who had had a bronchial carcinoid tumor resected nine years previously. The iris tumor was locally excised with a modified trabeculectomy approach. Histologic studies showed it to be a metastatic carcinoid tumor. Electron microscopy demonstrated typical dark and pale carcinoid cells with neurosecretory granules, basal bodies, and apical microvilli. The cisternae of the granular endoplasmic reticulum were disposed in a series of concentric rings encapsulating a central core of mitochondria. This unusual type of subcellular organization and specialization is probably a reflection of the slow-growing and highly differentiated nature of the iris tumor.
Original language | Undefined/Unknown |
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Pages (from-to) | 357-368 |
Number of pages | 12 |
Journal | American Journal of Ophthalmology |
Volume | 94 |
Issue number | 3 |
Publication status | Published - 01 Sept 1982 |
Bibliographical note
LR: 20041117; JID: 0370500; ppublishKeywords
- Adult
- Bronchial Neoplasms/surgery/ultrastructure
- Carcinoid Tumor/surgery/ultrastructure
- Female
- Humans
- Iris Diseases/pathology
- Microscopy, Electron
- Uveal Neoplasms/surgery/ultrastructure