An ultrastructural study of carcinoid tumor of the iris

D. B. Archer, T. A. Gardiner

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13 Citations (Scopus)


An iris tumor developed in a 37-year-old woman who had had a bronchial carcinoid tumor resected nine years previously. The iris tumor was locally excised with a modified trabeculectomy approach. Histologic studies showed it to be a metastatic carcinoid tumor. Electron microscopy demonstrated typical dark and pale carcinoid cells with neurosecretory granules, basal bodies, and apical microvilli. The cisternae of the granular endoplasmic reticulum were disposed in a series of concentric rings encapsulating a central core of mitochondria. This unusual type of subcellular organization and specialization is probably a reflection of the slow-growing and highly differentiated nature of the iris tumor.
Original languageUndefined/Unknown
Pages (from-to)357-368
Number of pages12
JournalAmerican Journal of Ophthalmology
Issue number3
Publication statusPublished - 01 Sept 1982

Bibliographical note

LR: 20041117; JID: 0370500; ppublish


  • Adult
  • Bronchial Neoplasms/surgery/ultrastructure
  • Carcinoid Tumor/surgery/ultrastructure
  • Female
  • Humans
  • Iris Diseases/pathology
  • Microscopy, Electron
  • Uveal Neoplasms/surgery/ultrastructure

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