Analysis of Histone Deacetylase 7 (HDAC7) Alternative Splicing and Its Role in Embryonic Stem Cell Differentiation Toward Smooth Muscle Lineage

Junyao Yang, Andriana Margariti, Lingfang Zeng

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

1 Citation (Scopus)

Abstract

Histone deacetylases (HDACs) have a central role in the regulation of gene expression, which undergoes alternative splicing during embryonic stem cell (ES) cell differentiation. Alternative splicing gives rise to vast diversity over gene information, arousing public concerns in the last decade. In this chapter, we describe a strategy to detect HDAC7 alternative splicing and analyze its function on ES cell differentiation.

Original languageEnglish
Title of host publicationHistone Deacetylases: Methods and Protocols
EditorsSibaji Sarkar
Place of PublicationNew York
PublisherSpringer
Pages95-108
Number of pages14
Volume1436
ISBN (Electronic)978-1-4939-3667-0
ISBN (Print)978-1-4939-3665-6
DOIs
Publication statusPublished - 01 Jun 2016

Publication series

NameMethods in Molecular Biology
PublisherSpringer
Volume1436
ISSN (Print)1064-3745

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