Antibiofilm activities of 1-alkyl-3-methylimidazolium chloride ionic liquids

Louise Carson; Peter K. W. Chau; Martyn J. Earle; Manuela A. Gilea; Brendan F. Gilmore; Sean P. Gorman; Maureen T. McCann; Kenneth R. Seddon

doi:10.1039/b821842k

Antibiofilm activities of 1-alkyl-3-methylimidazolium chloride ionic liquids

Louise Carson, Peter K. W. Chau, Martyn J. Earle, Manuela A. Gilea, Brendan F. Gilmore, Sean P. Gorman, Maureen T. McCann, Kenneth R. Seddon

Research output: Contribution to journal › Article › peer-review

199 Citations (Scopus)

Abstract

Microbial biofilms are ubiquitous in nature and represent the predominant mode of growth of microorganisms. A general characteristic of biofilm communities is that they tend to exhibit significant tolerance to antimicrobial challenge compared with planktonic bacteria of the same species The antibiofilm activity of a series of 1-alkyl-3-methylimidazolium chloride ionic liquids has been evaluated against a panel of clinically significant microbial pathogens, including MRSA. A comparison of antimicrobial activity against planktonic bacteria and established biofilms is presented. In general, these ionic liquids possess potent, broad spectrum antibiofilm activity.

Original language	English
Pages (from-to)	492-497
Number of pages	6
Journal	Green Chemistry
Volume	11
Issue number	4
Early online date	18 Feb 2009
DOIs	https://doi.org/10.1039/b821842k
Publication status	Published - 2009

ASJC Scopus subject areas

Environmental Chemistry
Pollution

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10.1039/b821842k

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title = "Antibiofilm activities of 1-alkyl-3-methylimidazolium chloride ionic liquids",

abstract = "Microbial biofilms are ubiquitous in nature and represent the predominant mode of growth of microorganisms. A general characteristic of biofilm communities is that they tend to exhibit significant tolerance to antimicrobial challenge compared with planktonic bacteria of the same species The antibiofilm activity of a series of 1-alkyl-3-methylimidazolium chloride ionic liquids has been evaluated against a panel of clinically significant microbial pathogens, including MRSA. A comparison of antimicrobial activity against planktonic bacteria and established biofilms is presented. In general, these ionic liquids possess potent, broad spectrum antibiofilm activity.",

author = "Louise Carson and Chau, {Peter K. W.} and Earle, {Martyn J.} and Gilea, {Manuela A.} and Gilmore, {Brendan F.} and Gorman, {Sean P.} and McCann, {Maureen T.} and Seddon, {Kenneth R.}",

year = "2009",

doi = "10.1039/b821842k",

language = "English",

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pages = "492--497",

journal = "Green Chemistry",

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T1 - Antibiofilm activities of 1-alkyl-3-methylimidazolium chloride ionic liquids

AU - Carson, Louise

AU - Chau, Peter K. W.

AU - Earle, Martyn J.

AU - Gilea, Manuela A.

AU - Gilmore, Brendan F.

AU - Gorman, Sean P.

AU - McCann, Maureen T.

AU - Seddon, Kenneth R.

PY - 2009

Y1 - 2009

N2 - Microbial biofilms are ubiquitous in nature and represent the predominant mode of growth of microorganisms. A general characteristic of biofilm communities is that they tend to exhibit significant tolerance to antimicrobial challenge compared with planktonic bacteria of the same species The antibiofilm activity of a series of 1-alkyl-3-methylimidazolium chloride ionic liquids has been evaluated against a panel of clinically significant microbial pathogens, including MRSA. A comparison of antimicrobial activity against planktonic bacteria and established biofilms is presented. In general, these ionic liquids possess potent, broad spectrum antibiofilm activity.

AB - Microbial biofilms are ubiquitous in nature and represent the predominant mode of growth of microorganisms. A general characteristic of biofilm communities is that they tend to exhibit significant tolerance to antimicrobial challenge compared with planktonic bacteria of the same species The antibiofilm activity of a series of 1-alkyl-3-methylimidazolium chloride ionic liquids has been evaluated against a panel of clinically significant microbial pathogens, including MRSA. A comparison of antimicrobial activity against planktonic bacteria and established biofilms is presented. In general, these ionic liquids possess potent, broad spectrum antibiofilm activity.

U2 - 10.1039/b821842k

DO - 10.1039/b821842k

M3 - Article

VL - 11

SP - 492

EP - 497

JO - Green Chemistry

JF - Green Chemistry

SN - 1463-9262

IS - 4

ER -