Antibodies to the structural polypeptides of measles virus following acute infection and in SSPE

A Trudgett, W J Bellini, E S Mingioli, D E McFarlin

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

A solid-phase radioimmunoassay was used to determine the specificity of IgG antibodies from normal sera, sera and CSF from patients with SSPE for the structural polypeptides of measles virus. The polypeptide specificity of antibodies from these sources were qualitatively similar; these results indicate antigenic cross-reactivity between SSPE-derived (Mantooth) and non-SSPE-derived strains of measles virus and stimulation of antibody formation by comparable antigens.
Original languageEnglish
Pages (from-to)652-6
Number of pages5
JournalClinical and experimental immunology
Volume39
Issue number3
Publication statusPublished - Mar 1980

Keywords

  • Adult
  • Antibodies, Viral
  • Antibody Specificity
  • Cross Reactions
  • Humans
  • Immunoglobulin G
  • Immunosorbent Techniques
  • Measles
  • Measles virus
  • Peptides
  • Subacute Sclerosing Panencephalitis

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