Antibodies to the structural polypeptides of measles virus following acute infection and in SSPE

A Trudgett; W J Bellini; E S Mingioli; D E McFarlin

Antibodies to the structural polypeptides of measles virus following acute infection and in SSPE

A Trudgett, W J Bellini, E S Mingioli, D E McFarlin

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

A solid-phase radioimmunoassay was used to determine the specificity of IgG antibodies from normal sera, sera and CSF from patients with SSPE for the structural polypeptides of measles virus. The polypeptide specificity of antibodies from these sources were qualitatively similar; these results indicate antigenic cross-reactivity between SSPE-derived (Mantooth) and non-SSPE-derived strains of measles virus and stimulation of antibody formation by comparable antigens.

Original language	English
Pages (from-to)	652-6
Number of pages	5
Journal	Clinical and Experimental Immunology
Volume	39
Issue number	3
Publication status	Published - Mar 1980

Keywords

Adult
Antibodies, Viral
Antibody Specificity
Cross Reactions
Humans
Immunoglobulin G
Immunosorbent Techniques
Measles
Measles virus
Peptides
Subacute Sclerosing Panencephalitis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Antibodies to the structural polypeptides of measles virus following acute infection and in SSPE",

abstract = "A solid-phase radioimmunoassay was used to determine the specificity of IgG antibodies from normal sera, sera and CSF from patients with SSPE for the structural polypeptides of measles virus. The polypeptide specificity of antibodies from these sources were qualitatively similar; these results indicate antigenic cross-reactivity between SSPE-derived (Mantooth) and non-SSPE-derived strains of measles virus and stimulation of antibody formation by comparable antigens.",

keywords = "Adult, Antibodies, Viral, Antibody Specificity, Cross Reactions, Humans, Immunoglobulin G, Immunosorbent Techniques, Measles, Measles virus, Peptides, Subacute Sclerosing Panencephalitis",

author = "A Trudgett and Bellini, {W J} and Mingioli, {E S} and McFarlin, {D E}",

year = "1980",

month = mar,

language = "English",

volume = "39",

pages = "652--6",

journal = "Clinical and Experimental Immunology",

issn = "0009-9104",

publisher = "Wiley-Blackwell",

number = "3",

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TY - JOUR

T1 - Antibodies to the structural polypeptides of measles virus following acute infection and in SSPE

AU - Trudgett, A

AU - Bellini, W J

AU - Mingioli, E S

AU - McFarlin, D E

PY - 1980/3

Y1 - 1980/3

N2 - A solid-phase radioimmunoassay was used to determine the specificity of IgG antibodies from normal sera, sera and CSF from patients with SSPE for the structural polypeptides of measles virus. The polypeptide specificity of antibodies from these sources were qualitatively similar; these results indicate antigenic cross-reactivity between SSPE-derived (Mantooth) and non-SSPE-derived strains of measles virus and stimulation of antibody formation by comparable antigens.

AB - A solid-phase radioimmunoassay was used to determine the specificity of IgG antibodies from normal sera, sera and CSF from patients with SSPE for the structural polypeptides of measles virus. The polypeptide specificity of antibodies from these sources were qualitatively similar; these results indicate antigenic cross-reactivity between SSPE-derived (Mantooth) and non-SSPE-derived strains of measles virus and stimulation of antibody formation by comparable antigens.

KW - Adult

KW - Antibodies, Viral

KW - Antibody Specificity

KW - Cross Reactions

KW - Humans

KW - Immunoglobulin G

KW - Immunosorbent Techniques

KW - Measles

KW - Measles virus

KW - Peptides

KW - Subacute Sclerosing Panencephalitis

M3 - Article

C2 - 6991172

VL - 39

SP - 652

EP - 656

JO - Clinical and Experimental Immunology

JF - Clinical and Experimental Immunology

SN - 0009-9104

IS - 3

ER -

Antibodies to the structural polypeptides of measles virus following acute infection and in SSPE

Abstract

Keywords

UN SDGs

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