Abstract
The quantitative assessment of apoptotic index (AI) and mitotic index (MI) and the immunoreactivity of p53, bcl-2, p21, and mdm2 were examined in tumour and adjacent normal tissue samples from 30 patients with colonic and 22 with rectal adenocarcinoma. Individual features and combined profiles were correlated with clinicopathological parameters and patient survival data to assess their prognostic value. Increased AI was significantly associated with increased bcl-2 expression (p
Original language | English |
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Pages (from-to) | 436-443 |
Number of pages | 8 |
Journal | Journal of Pathology |
Volume | 194(4) |
Issue number | 4 |
DOIs | |
Publication status | Published - Aug 2001 |
ASJC Scopus subject areas
- Pathology and Forensic Medicine