Apoptotic Engulfment Pathway and Schizophrenia

X.N. Chen; C.E. Sun; Q. Chen; Francis O'Neill; D. Walsh; A.H. Fanous; K.V. Chowdari; V.L. Nimgaonkar; A. Scott; S.G. Schwab; D.B. Wildenauer; R.L. Che; W. Tang; Y.Y. Shi; L. He; X.J. Luo; B. Su; T.L. Edwards; Z.M. Zhao; K.S. Kendler

doi:10.1371/journal.pone.0006875

Apoptotic Engulfment Pathway and Schizophrenia

X.N. Chen, C.E. Sun, Q. Chen, Francis O'Neill, D. Walsh, A.H. Fanous, K.V. Chowdari, V.L. Nimgaonkar, A. Scott, S.G. Schwab, D.B. Wildenauer, R.L. Che, W. Tang, Y.Y. Shi, L. He, X.J. Luo, B. Su, T.L. Edwards, Z.M. Zhao, K.S. Kendler

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

Background: Apoptosis has been speculated to be involved in schizophrenia. In a previously study, we reported the association of the MEGF10 gene with the disease. In this study, we followed the apoptotic engulfment pathway involving the MEGF10, GULP1, ABCA1 and ABCA7 genes and tested their association with the disease.

Original language	English
Article number	e6875
Journal	PLoS ONE
Volume	4
Issue number	9
DOIs	https://doi.org/10.1371/journal.pone.0006875
Publication status	Published - 01 Sep 2009

ASJC Scopus subject areas

Agricultural and Biological Sciences(all)
Biochemistry, Genetics and Molecular Biology(all)
Medicine(all)

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Chen, X. N., Sun, C. E., Chen, Q., O'Neill, F., Walsh, D., Fanous, A. H., Chowdari, K. V., Nimgaonkar, V. L., Scott, A., Schwab, S. G., Wildenauer, D. B., Che, R. L., Tang, W., Shi, Y. Y., He, L., Luo, X. J., Su, B., Edwards, T. L., Zhao, Z. M., & Kendler, K. S. (2009). Apoptotic Engulfment Pathway and Schizophrenia. PLoS ONE, 4(9), [e6875]. https://doi.org/10.1371/journal.pone.0006875

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abstract = "Background: Apoptosis has been speculated to be involved in schizophrenia. In a previously study, we reported the association of the MEGF10 gene with the disease. In this study, we followed the apoptotic engulfment pathway involving the MEGF10, GULP1, ABCA1 and ABCA7 genes and tested their association with the disease.",

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Apoptotic Engulfment Pathway and Schizophrenia. / Chen, X.N.; Sun, C.E.; Chen, Q.; O'Neill, Francis; Walsh, D.; Fanous, A.H.; Chowdari, K.V.; Nimgaonkar, V.L.; Scott, A.; Schwab, S.G.; Wildenauer, D.B.; Che, R.L.; Tang, W.; Shi, Y.Y.; He, L.; Luo, X.J.; Su, B.; Edwards, T.L.; Zhao, Z.M.; Kendler, K.S.

In: PLoS ONE, Vol. 4, No. 9, e6875, 01.09.2009.

Research output: Contribution to journal › Article › peer-review

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T1 - Apoptotic Engulfment Pathway and Schizophrenia

AU - Chen, X.N.

AU - Sun, C.E.

AU - Chen, Q.

AU - O'Neill, Francis

AU - Walsh, D.

AU - Fanous, A.H.

AU - Chowdari, K.V.

AU - Nimgaonkar, V.L.

AU - Scott, A.

AU - Schwab, S.G.

AU - Wildenauer, D.B.

AU - Che, R.L.

AU - Tang, W.

AU - Shi, Y.Y.

AU - He, L.

AU - Luo, X.J.

AU - Su, B.

AU - Edwards, T.L.

AU - Zhao, Z.M.

AU - Kendler, K.S.

PY - 2009/9/1

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AB - Background: Apoptosis has been speculated to be involved in schizophrenia. In a previously study, we reported the association of the MEGF10 gene with the disease. In this study, we followed the apoptotic engulfment pathway involving the MEGF10, GULP1, ABCA1 and ABCA7 genes and tested their association with the disease.

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