Application of ultrasound for sonodynamic photocatalysis

Paul A. Campbell*, Ian Campbell, Pauline Axford, Yaoyao Cui, Peter K J Robertson

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Ultrasound has long been recognized as a means of effecting change at the cellular and tissue levels [1-3], which may be enhanced in the presence of photosensitive agents [4-6]. During insonation, the presence of bubbles can also play a role, creating strong microstreaming effects in solution and in more dramatic circumstances leading to the formation of energetic microjets [7], plasmas [8], and the production of other highly reactive species [9]. Such sonodynamic activity has generated particular excitement in the medical community as it Moreover the dual role for microbubbles as both an adjunct to therapy and a diagnostic echogenicity enhancer has seen industry take a proactive role in their development. In the present paper we studied the role of ultrasound driven sonoluminescent light on the degradation of a fluorescent test species (rhodamine) in the presence of an archetypal photocatalyst material, TiO 2, with a view to exploring its exploitation potential for downstream medical applications. We found that, whilst the efficiency of this process is seen to be low compared with conventional ultra-violet sources, we advocate the further exploration of the sonoluminescent approach given its potential for non-invasive applications. A strategy for enhancing the effect is also suggested. 

Original languageEnglish
Title of host publicationProceedings of 2011 International Symposium on Bioelectronics and Bioinformatics (ISBB)
PublisherInstitute of Electrical and Electronics Engineers Inc.
Number of pages4
ISBN (Print)9781457700767
Publication statusPublished - 2011
Event2nd International Symposium on Bioelectronics and Bioinformatics, ISBB 2011 - Suzhou, China
Duration: 03 Nov 201105 Nov 2011


Conference2nd International Symposium on Bioelectronics and Bioinformatics, ISBB 2011

ASJC Scopus subject areas

  • Biomedical Engineering
  • Electrical and Electronic Engineering
  • Health Informatics


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