Aromatic dioxygenases: Molecular biocatalysis and applications

Derek R. Boyd, Narain D. Sharma, C. C R Allen

Research output: Contribution to journalArticlepeer-review

147 Citations (Scopus)


Aromatic dioxygenases have been found to catalyse single and tandem oxidation reactions of conjugated polyenes. Rational selection and design of dioxygenases, allied to substrate shape, size and substitution pattern, has been used to control regiochemistry and stereochemistry during the oxygenation process. The resulting enantiopure bioproducts have been increasingly utilised as precursors for new and alternative routes in chiral synthesis.
Original languageEnglish
Pages (from-to)564-573
Number of pages10
JournalCurrent opinion in biotechnology
Issue number6
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Biotechnology

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