Assessment of the feed additives calcium d-pantothenate and d-panthenol for all animal species for the renewal of their authorisation (DSM Nutritional products Ltd)

Roberto Edoardo Villa; Giovanna Azimonti; Eleftherios Bonos; Henrik Christensen; Mojca Durjava; Birgit Dusemund; Ronette Gehring; Boet Glandorf; Maryline Kouba; Marta López-Alonso; Francesca Marcon; Carlo Nebbia; Alena Pechová; Miguel Prieto-Maradona; Ilen Röhe; Katerina Theodoridou; Jaume Galobart; Orsolya Holczknecht; Fabiola Pizzo; Anita Radovnikovic; Maria Vittoria Vettori; Angelica Amaduzzi; EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)

doi:10.2903/j.efsa.2025.9252

Assessment of the feed additives calcium d-pantothenate and d-panthenol for all animal species for the renewal of their authorisation (DSM Nutritional products Ltd)

Roberto Edoardo Villa
, Giovanna Azimonti
, Eleftherios Bonos
, Henrik Christensen
, Mojca Durjava
, Birgit Dusemund
, Ronette Gehring
, Boet Glandorf
, Maryline Kouba
, Marta López-Alonso
, Francesca Marcon
, Carlo Nebbia
, Alena Pechová
, Miguel Prieto-Maradona
, Ilen Röhe
, Katerina Theodoridou
, Jaume Galobart
, Orsolya Holczknecht
, Fabiola Pizzo
, Anita Radovnikovic

Maria Vittoria Vettori, Angelica Amaduzzi, EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

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Abstract

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of calcium d-pantothenate and d-panthenol for the renewal of its authorisation. Calcium d-pantothenate and d-panthenol are currently authorised as nutritional feed additives for all animal species and categories. The FEEDAP Panel concluded that the use of calcium d-pantothenate and d-panthenol as feed additive in animal nutrition under the conditions of use is of no concern for the safety of the target species, the consumer and the environment. Calcium d-pantothenate is not irritant to skin and eyes and is not a dermal sensitiser. d-panthenol is considered to be a skin and eye irritant and a dermal and respiratory sensitiser. There is no need for assessing the efficacy of the additive in the context of this renewal of the authorisation.

Original language	English
Article number	e9252
Number of pages	9
Journal	EFSA Journal
Volume	23
Issue number	2
DOIs	https://doi.org/10.2903/j.efsa.2025.9252
Publication status	Published - 27 Feb 2025

Bibliographical note

Publisher Copyright:
© 2025 European Food Safety Authority. EFSA Journal published by Wiley-VCH GmbH on behalf of European Food Safety Authority.

Keywords

calcium d-pantothenate
d-panthenol
efficacy
nutritional additives
safety
vitamin

ASJC Scopus subject areas

Parasitology
Food Science
Microbiology
Animal Science and Zoology
veterinary (miscalleneous)
Plant Science

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10.2903/j.efsa.2025.9252Licence: CC BY-ND

Assessment of the feed additives calcium d-pantothenate and d-panthenol for all animal species for the renewal of their authorisation (DSM Nutritional products Ltd)
© 2025 EFSA and The Authors. This is an open access article under the terms of the Creative Commons Attribution-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made
Final published version, 153 KBLicence: CC BY-ND

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Villa, R. E., Azimonti, G., Bonos, E., Christensen, H., Durjava, M., Dusemund, B., Gehring, R., Glandorf, B., Kouba, M., López-Alonso, M., Marcon, F., Nebbia, C., Pechová, A., Prieto-Maradona, M., Röhe, I., Theodoridou, K., Galobart, J., Holczknecht, O., Pizzo, F., ... EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) (2025). Assessment of the feed additives calcium d-pantothenate and d-panthenol for all animal species for the renewal of their authorisation (DSM Nutritional products Ltd). EFSA Journal, 23(2), Article e9252. https://doi.org/10.2903/j.efsa.2025.9252

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abstract = "Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of calcium d-pantothenate and d-panthenol for the renewal of its authorisation. Calcium d-pantothenate and d-panthenol are currently authorised as nutritional feed additives for all animal species and categories. The FEEDAP Panel concluded that the use of calcium d-pantothenate and d-panthenol as feed additive in animal nutrition under the conditions of use is of no concern for the safety of the target species, the consumer and the environment. Calcium d-pantothenate is not irritant to skin and eyes and is not a dermal sensitiser. d-panthenol is considered to be a skin and eye irritant and a dermal and respiratory sensitiser. There is no need for assessing the efficacy of the additive in the context of this renewal of the authorisation.",

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Villa, RE, Azimonti, G, Bonos, E, Christensen, H, Durjava, M, Dusemund, B, Gehring, R, Glandorf, B, Kouba, M, López-Alonso, M, Marcon, F, Nebbia, C, Pechová, A, Prieto-Maradona, M, Röhe, I, Theodoridou, K, Galobart, J, Holczknecht, O, Pizzo, F, Radovnikovic, A, Vettori, MV, Amaduzzi, A & EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) 2025, 'Assessment of the feed additives calcium d-pantothenate and d-panthenol for all animal species for the renewal of their authorisation (DSM Nutritional products Ltd)', EFSA Journal, vol. 23, no. 2, e9252. https://doi.org/10.2903/j.efsa.2025.9252

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AU - Azimonti, Giovanna

AU - Bonos, Eleftherios

AU - Christensen, Henrik

AU - Durjava, Mojca

AU - Dusemund, Birgit

AU - Gehring, Ronette

AU - Glandorf, Boet

AU - Kouba, Maryline

AU - López-Alonso, Marta

AU - Marcon, Francesca

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AU - Pechová, Alena

AU - Prieto-Maradona, Miguel

AU - Röhe, Ilen

AU - Theodoridou, Katerina

AU - Galobart, Jaume

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AU - Pizzo, Fabiola

AU - Radovnikovic, Anita

AU - Vettori, Maria Vittoria

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AB - Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of calcium d-pantothenate and d-panthenol for the renewal of its authorisation. Calcium d-pantothenate and d-panthenol are currently authorised as nutritional feed additives for all animal species and categories. The FEEDAP Panel concluded that the use of calcium d-pantothenate and d-panthenol as feed additive in animal nutrition under the conditions of use is of no concern for the safety of the target species, the consumer and the environment. Calcium d-pantothenate is not irritant to skin and eyes and is not a dermal sensitiser. d-panthenol is considered to be a skin and eye irritant and a dermal and respiratory sensitiser. There is no need for assessing the efficacy of the additive in the context of this renewal of the authorisation.

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KW - d-panthenol

KW - efficacy

KW - nutritional additives

KW - safety

KW - vitamin

U2 - 10.2903/j.efsa.2025.9252

DO - 10.2903/j.efsa.2025.9252

M3 - Article

AN - SCOPUS:86000013251

SN - 1831-4732

VL - 23

JO - EFSA Journal

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IS - 2

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ER -

Assessment of the feed additives calcium d-pantothenate and d-panthenol for all animal species for the renewal of their authorisation (DSM Nutritional products Ltd)

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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