Activities per year
Abstract
Deposition of tau-tangles is an early marker for the development of Alzheimer’s disease (AD). Here we show that these aggregates of phosphorylated tau protein are associated with the calcification of cell nuclei and cell projections, especially in the middle temporal, superior temporal and parahippocampal gyri. This calcification is related to the aetiology of the disease, shedding new light on the mechanisms involved in AD and potentially providing a new detection method for AD progression.
### Competing Interest Statement
The authors have declared no competing interest.
Original language | English |
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Pages | 2020.06.15.148353 |
DOIs | |
Publication status | Published - 2020 |
Publication series
Name | bioRxiv |
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Publisher | Cold Spring Harbor Laboratory Press |
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Dive into the research topics of 'Association of cellular and subcellular calcification with phosphorylated tau in the brains of Alzheimer’s disease patients'. Together they form a unique fingerprint.Activities
- 1 Participation in conference
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Budapest Biannual Calcification meeting
Lengyel, I. (Participant)
01 Oct 2023 → 03 Oct 2023Activity: Participating in or organising an event types › Participation in conference