Association of dietary flavonoids intake with prevalence of type 2 diabetes mellitus and cardiovascular disease risk factors in Korean women aged ≥ 30

Aswathy Vijayakumar, Ji Soo Oh, Hyesook Kim, Oran Kwon, Yangha Kim, Namsoo Chang

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The purpose of this study was to investigate the association between dietary flavonoid intake and the prevalence of type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) risk factors among Korean women aged ≥30 y. This study used data collected from the 2007-2012 Korean National Health and Nutrition Examination Survey. We excluded subjects who had energy intake <500 kcal or ≥5,000 kcal, were diagnosed with chronic disease, were taking medication, or were pregnant or lactating. The final subjects included 7,963 women, and they were divided into 2 groups, the normal fasting glucose (NFG) group (n=7,738) and the T2DM group (n=225). The intake of flavonoids was estimated on the basis of the flavonoid database. After adjustment for confounding factors, the mean intakes of fruits, anthocyanidins, and flavones were significantly lower in the T2DM group than in the NFG group. In multiple regression analysis, the dietary flavone intake was negatively associated with systolic blood pressure, triglyceride, TG/HDL-cholesterol, and homesostatic model assessment of insulin resistance. Daily intake of flavones above the 25th percentile was associated with a lower prevalence of T2DM compared with intake below the 25th percentile (OR=0.593, 95% confidence interval (CI): 0.414-0.847). These study results showed that dietary flavone intake may have some beneficial effects in reducing CVD risks and prevalence of T2DM in Korean women.
Original languageEnglish
Pages (from-to)51-58
Number of pages8
JournalJournal of Nutritional Science and Vitaminology
Volume63
Issue number1
DOIs
Publication statusPublished - 28 Mar 2017
Externally publishedYes

Fingerprint

Flavonoids
flavone
Type 2 Diabetes Mellitus
Cardiovascular Diseases
Flavones
Fasting
Blood Pressure
Glucose
Anthocyanins
Nutrition Surveys
Energy Intake
HDL Cholesterol
Insulin Resistance
Fruit
Triglycerides
Chronic Disease
Regression Analysis
Databases
Confidence Intervals

Keywords

  • Flavonoids
  • Type 2 diabetes mellitus
  • cardiovascular disease
  • Korean women

Cite this

@article{6ad367fc67f24353bd2d23c5b5c83bc2,
title = "Association of dietary flavonoids intake with prevalence of type 2 diabetes mellitus and cardiovascular disease risk factors in Korean women aged ≥ 30",
abstract = "The purpose of this study was to investigate the association between dietary flavonoid intake and the prevalence of type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) risk factors among Korean women aged ≥30 y. This study used data collected from the 2007-2012 Korean National Health and Nutrition Examination Survey. We excluded subjects who had energy intake <500 kcal or ≥5,000 kcal, were diagnosed with chronic disease, were taking medication, or were pregnant or lactating. The final subjects included 7,963 women, and they were divided into 2 groups, the normal fasting glucose (NFG) group (n=7,738) and the T2DM group (n=225). The intake of flavonoids was estimated on the basis of the flavonoid database. After adjustment for confounding factors, the mean intakes of fruits, anthocyanidins, and flavones were significantly lower in the T2DM group than in the NFG group. In multiple regression analysis, the dietary flavone intake was negatively associated with systolic blood pressure, triglyceride, TG/HDL-cholesterol, and homesostatic model assessment of insulin resistance. Daily intake of flavones above the 25th percentile was associated with a lower prevalence of T2DM compared with intake below the 25th percentile (OR=0.593, 95{\%} confidence interval (CI): 0.414-0.847). These study results showed that dietary flavone intake may have some beneficial effects in reducing CVD risks and prevalence of T2DM in Korean women.",
keywords = "Flavonoids, Type 2 diabetes mellitus, cardiovascular disease, Korean women",
author = "Aswathy Vijayakumar and Oh, {Ji Soo} and Hyesook Kim and Oran Kwon and Yangha Kim and Namsoo Chang",
year = "2017",
month = "3",
day = "28",
doi = "10.3177/jnsv.63.51",
language = "English",
volume = "63",
pages = "51--58",
journal = "Journal of Nutritional Science and Vitaminology",
issn = "1881-7742",
publisher = "Center for Academic Publications Japan",
number = "1",

}

Association of dietary flavonoids intake with prevalence of type 2 diabetes mellitus and cardiovascular disease risk factors in Korean women aged ≥ 30. / Vijayakumar, Aswathy; Oh, Ji Soo; Kim, Hyesook ; Kwon, Oran; Kim, Yangha; Chang, Namsoo .

In: Journal of Nutritional Science and Vitaminology, Vol. 63, No. 1, 28.03.2017, p. 51-58.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Association of dietary flavonoids intake with prevalence of type 2 diabetes mellitus and cardiovascular disease risk factors in Korean women aged ≥ 30

AU - Vijayakumar, Aswathy

AU - Oh, Ji Soo

AU - Kim, Hyesook

AU - Kwon, Oran

AU - Kim, Yangha

AU - Chang, Namsoo

PY - 2017/3/28

Y1 - 2017/3/28

N2 - The purpose of this study was to investigate the association between dietary flavonoid intake and the prevalence of type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) risk factors among Korean women aged ≥30 y. This study used data collected from the 2007-2012 Korean National Health and Nutrition Examination Survey. We excluded subjects who had energy intake <500 kcal or ≥5,000 kcal, were diagnosed with chronic disease, were taking medication, or were pregnant or lactating. The final subjects included 7,963 women, and they were divided into 2 groups, the normal fasting glucose (NFG) group (n=7,738) and the T2DM group (n=225). The intake of flavonoids was estimated on the basis of the flavonoid database. After adjustment for confounding factors, the mean intakes of fruits, anthocyanidins, and flavones were significantly lower in the T2DM group than in the NFG group. In multiple regression analysis, the dietary flavone intake was negatively associated with systolic blood pressure, triglyceride, TG/HDL-cholesterol, and homesostatic model assessment of insulin resistance. Daily intake of flavones above the 25th percentile was associated with a lower prevalence of T2DM compared with intake below the 25th percentile (OR=0.593, 95% confidence interval (CI): 0.414-0.847). These study results showed that dietary flavone intake may have some beneficial effects in reducing CVD risks and prevalence of T2DM in Korean women.

AB - The purpose of this study was to investigate the association between dietary flavonoid intake and the prevalence of type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) risk factors among Korean women aged ≥30 y. This study used data collected from the 2007-2012 Korean National Health and Nutrition Examination Survey. We excluded subjects who had energy intake <500 kcal or ≥5,000 kcal, were diagnosed with chronic disease, were taking medication, or were pregnant or lactating. The final subjects included 7,963 women, and they were divided into 2 groups, the normal fasting glucose (NFG) group (n=7,738) and the T2DM group (n=225). The intake of flavonoids was estimated on the basis of the flavonoid database. After adjustment for confounding factors, the mean intakes of fruits, anthocyanidins, and flavones were significantly lower in the T2DM group than in the NFG group. In multiple regression analysis, the dietary flavone intake was negatively associated with systolic blood pressure, triglyceride, TG/HDL-cholesterol, and homesostatic model assessment of insulin resistance. Daily intake of flavones above the 25th percentile was associated with a lower prevalence of T2DM compared with intake below the 25th percentile (OR=0.593, 95% confidence interval (CI): 0.414-0.847). These study results showed that dietary flavone intake may have some beneficial effects in reducing CVD risks and prevalence of T2DM in Korean women.

KW - Flavonoids

KW - Type 2 diabetes mellitus

KW - cardiovascular disease

KW - Korean women

U2 - 10.3177/jnsv.63.51

DO - 10.3177/jnsv.63.51

M3 - Article

VL - 63

SP - 51

EP - 58

JO - Journal of Nutritional Science and Vitaminology

JF - Journal of Nutritional Science and Vitaminology

SN - 1881-7742

IS - 1

ER -