Association of the G4 rotavirus genotype with gastroenteritis in adults

S.A. Feeney, S.J. Mitchell, F. Mitchell, D.E. Wyatt, Derek Fairley, Conall McCaughey, Peter Coyle, H.J. O'Neill

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26 Citations (Scopus)

Abstract

Rotavirus is the most common etiological cause of acute viral gastroenteritis in infants and young children worldwide, yet its role in the adult population is less well understood. We have recently identified rotavirus as the causative agent of severe diarrhea in adults, specifically in two gastroenteritis outbreaks in separate care for the elderly homes. Strain typing has shown the continued presence of P[8]G1, the emergence of P[8]G9, and the reemergence of P[8]G4. A total of 26 community cases and 6 outbreak cases of rotavirus infection, positive via a molecular screening assay, were subsequently amplified using VP4 and VP7 specific primers (Con2/Con3 and 1A/1B primer sets, respectively). The age range of patients investigated was from
Original languageEnglish
Pages (from-to)1119-1123
Number of pages5
JournalJournal of Medical Virology
Volume78
Issue number8
DOIs
Publication statusPublished - Aug 2006

ASJC Scopus subject areas

  • Virology

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    Feeney, S. A., Mitchell, S. J., Mitchell, F., Wyatt, D. E., Fairley, D., McCaughey, C., Coyle, P., & O'Neill, H. J. (2006). Association of the G4 rotavirus genotype with gastroenteritis in adults. Journal of Medical Virology, 78(8), 1119-1123. https://doi.org/10.1002/jmv.20671