Abstract
4-Amino-5-hexynoic acid is efficiently synthesised in eight steps (overall yield 10%) from commercially available (S)-glutamic acid. The key step was conversion of an aldehyde to an acetylene using diethylmethydiazophosphonate.
Original language | English |
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Pages (from-to) | 239-244 |
Number of pages | 6 |
Journal | Tetrahedron-Asymmetry |
Volume | 6 |
Issue number | 1 |
Publication status | Published - Jan 1995 |
Keywords
- GABA
- AMINOTRANSFERASE
- INHIBITORS
- DERIVATIVES
- MECHANISM
- REAGENT