Bacteriophages for Biofilm Eradication

Research output: Contribution to conferencePoster

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Abstract

Bacteriophages or phages are a unique type of virus that recognize a specific type of bacteria and then infect, replicate and kill the host via cell lysis. The application of phages and their enzymes for treating bacterial biofilms has recently gained significant interest due to a number of significant advantages compared to traditional antibiotics, including high specificity and efficacy, low immunogenicity and production costs.
Proteus mirabilis, Stenotrophomonas maltophilia and Pseudomonas aeruginosa are all clinically relevant microorganisms associated with biofilm formation and thus there is great difficulty treating such infections.
With the increasing number of multi-drug resistant strains being reported the time for novel antimicrobial agents is now and thus we propose the use of bacteriophages to treat the said bacterial species’ biofilms.
Original languageEnglish
Publication statusPublished - 20 Sep 2019
EventSchool of Pharmacy Postgraduate Research Symposium - Riddel Hall, Belfast, United Kingdom
Duration: 17 Jun 2019 → …

Conference

ConferenceSchool of Pharmacy Postgraduate Research Symposium
CountryUnited Kingdom
CityBelfast
Period17/06/2019 → …

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Biofilms
Bacteriophages
Stenotrophomonas maltophilia
Proteus mirabilis
Anti-Infective Agents
Pseudomonas aeruginosa
Anti-Bacterial Agents
Viruses
Bacteria
Costs and Cost Analysis
Enzymes
Infection
Pharmaceutical Preparations

Cite this

Rice, C., Skvortsov, T., Kumaresan, D., Flynn, P., Gilmore, B., & Kulakov, L. (2019). Bacteriophages for Biofilm Eradication. Poster session presented at School of Pharmacy Postgraduate Research Symposium, Belfast, United Kingdom.
Rice, Cormac ; Skvortsov, Timofey ; Kumaresan, Deepak ; Flynn, Padrig ; Gilmore, Brendan ; Kulakov, Leonid. / Bacteriophages for Biofilm Eradication. Poster session presented at School of Pharmacy Postgraduate Research Symposium, Belfast, United Kingdom.
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title = "Bacteriophages for Biofilm Eradication",
abstract = "Bacteriophages or phages are a unique type of virus that recognize a specific type of bacteria and then infect, replicate and kill the host via cell lysis. The application of phages and their enzymes for treating bacterial biofilms has recently gained significant interest due to a number of significant advantages compared to traditional antibiotics, including high specificity and efficacy, low immunogenicity and production costs. Proteus mirabilis, Stenotrophomonas maltophilia and Pseudomonas aeruginosa are all clinically relevant microorganisms associated with biofilm formation and thus there is great difficulty treating such infections. With the increasing number of multi-drug resistant strains being reported the time for novel antimicrobial agents is now and thus we propose the use of bacteriophages to treat the said bacterial species’ biofilms.",
author = "Cormac Rice and Timofey Skvortsov and Deepak Kumaresan and Padrig Flynn and Brendan Gilmore and Leonid Kulakov",
year = "2019",
month = "9",
day = "20",
language = "English",
note = "School of Pharmacy Postgraduate Research Symposium ; Conference date: 17-06-2019",

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Rice, C, Skvortsov, T, Kumaresan, D, Flynn, P, Gilmore, B & Kulakov, L 2019, 'Bacteriophages for Biofilm Eradication', School of Pharmacy Postgraduate Research Symposium, Belfast, United Kingdom, 17/06/2019.

Bacteriophages for Biofilm Eradication. / Rice, Cormac; Skvortsov, Timofey; Kumaresan, Deepak; Flynn, Padrig; Gilmore, Brendan; Kulakov, Leonid.

2019. Poster session presented at School of Pharmacy Postgraduate Research Symposium, Belfast, United Kingdom.

Research output: Contribution to conferencePoster

TY - CONF

T1 - Bacteriophages for Biofilm Eradication

AU - Rice, Cormac

AU - Skvortsov, Timofey

AU - Kumaresan, Deepak

AU - Flynn, Padrig

AU - Gilmore, Brendan

AU - Kulakov, Leonid

PY - 2019/9/20

Y1 - 2019/9/20

N2 - Bacteriophages or phages are a unique type of virus that recognize a specific type of bacteria and then infect, replicate and kill the host via cell lysis. The application of phages and their enzymes for treating bacterial biofilms has recently gained significant interest due to a number of significant advantages compared to traditional antibiotics, including high specificity and efficacy, low immunogenicity and production costs. Proteus mirabilis, Stenotrophomonas maltophilia and Pseudomonas aeruginosa are all clinically relevant microorganisms associated with biofilm formation and thus there is great difficulty treating such infections. With the increasing number of multi-drug resistant strains being reported the time for novel antimicrobial agents is now and thus we propose the use of bacteriophages to treat the said bacterial species’ biofilms.

AB - Bacteriophages or phages are a unique type of virus that recognize a specific type of bacteria and then infect, replicate and kill the host via cell lysis. The application of phages and their enzymes for treating bacterial biofilms has recently gained significant interest due to a number of significant advantages compared to traditional antibiotics, including high specificity and efficacy, low immunogenicity and production costs. Proteus mirabilis, Stenotrophomonas maltophilia and Pseudomonas aeruginosa are all clinically relevant microorganisms associated with biofilm formation and thus there is great difficulty treating such infections. With the increasing number of multi-drug resistant strains being reported the time for novel antimicrobial agents is now and thus we propose the use of bacteriophages to treat the said bacterial species’ biofilms.

M3 - Poster

ER -

Rice C, Skvortsov T, Kumaresan D, Flynn P, Gilmore B, Kulakov L. Bacteriophages for Biofilm Eradication. 2019. Poster session presented at School of Pharmacy Postgraduate Research Symposium, Belfast, United Kingdom.