Basiepidermal nervous system in Nemertoderma westbladi (Nemertodermatida): GYIRFamide immunoreactivity

O.I. Raikova, M. Reuter, M.K.S. Gustafsson, Aaron Maule, David Halton, U. Jondelius

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)


The Nemertodermatida are a small group of microscopic marine worms. Recent molecular studies have demonstrated that they are likely to be the earliest extant bilaterian animals. What was the nervous system (NS) of a bilaterian ancestor like? In order to answer that question, the NS of Nemertoderma westbladi was investigated by means of indirect immunofluorescence technique and confocal scanning laser microscopy. The antibodies to a flatworm neuropeptide GYIRFamide were used in combination with anti-serotonin antibodies and phalloidin-TRITC staining. The immunostaining revealed an entirely basiepidermal NS. A ring lying outside the body wall musculature at the level of the statocyst forms the only centralisation, the
Original languageEnglish
Pages (from-to)75-86
Number of pages12
JournalJournal of Zoology
Issue number1
Publication statusPublished - 2004

ASJC Scopus subject areas

  • Animal Science and Zoology

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