Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

H. Huynh; P.K.H. Chow; N. Palanisamy; Manuel Salto-Tellez; B.C. Goh; C.K. Lee; A. Somani; H.S. Lee; R. Kalpana; K. Yu; P.H. Tan; J. Wu; R. Soong; M.H. Lee; H. Hor; K.C. Soo; H.C. Toh; P. Tan

doi:10.1016/j.jhep.2008.02.022

Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

H. Huynh, P.K.H. Chow, N. Palanisamy, Manuel Salto-Tellez, B.C. Goh, C.K. Lee, A. Somani, H.S. Lee, R. Kalpana, K. Yu, P.H. Tan, J. Wu, R. Soong, M.H. Lee, H. Hor, K.C. Soo, H.C. Toh, P. Tan

Research output: Contribution to journal › Article › peer-review

70 Citations (Scopus)

Abstract

Background/Aims: Hepatocellular carcinoma is a leading cause of global cancer mortality, with standard chemotherapy being minimally effective in prolonging survival. We investigated if combined targeting of vascular endothelial growth factor protein and expression might affect hepatocellular carcinoma growth and angiogenesis.

Original language	English
Pages (from-to)	52-60
Number of pages	9
Journal	Journal of Hepatology
Volume	49
Issue number	1
DOIs	https://doi.org/10.1016/j.jhep.2008.02.022
Publication status	Published - Jul 2008

ASJC Scopus subject areas

Gastroenterology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jhep.2008.02.022

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Huynh, H., Chow, P. K. H., Palanisamy, N., Salto-Tellez, M., Goh, B. C., Lee, C. K., Somani, A., Lee, H. S., Kalpana, R., Yu, K., Tan, P. H., Wu, J., Soong, R., Lee, M. H., Hor, H., Soo, K. C., Toh, H. C., & Tan, P. (2008). Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma. Journal of Hepatology, 49(1), 52-60. https://doi.org/10.1016/j.jhep.2008.02.022

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title = "Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma",

abstract = "Background/Aims: Hepatocellular carcinoma is a leading cause of global cancer mortality, with standard chemotherapy being minimally effective in prolonging survival. We investigated if combined targeting of vascular endothelial growth factor protein and expression might affect hepatocellular carcinoma growth and angiogenesis.",

author = "H. Huynh and P.K.H. Chow and N. Palanisamy and Manuel Salto-Tellez and B.C. Goh and C.K. Lee and A. Somani and H.S. Lee and R. Kalpana and K. Yu and P.H. Tan and J. Wu and R. Soong and M.H. Lee and H. Hor and K.C. Soo and H.C. Toh and P. Tan",

year = "2008",

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doi = "10.1016/j.jhep.2008.02.022",

language = "English",

volume = "49",

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Huynh, H, Chow, PKH, Palanisamy, N, Salto-Tellez, M, Goh, BC, Lee, CK, Somani, A, Lee, HS, Kalpana, R, Yu, K, Tan, PH, Wu, J, Soong, R, Lee, MH, Hor, H, Soo, KC, Toh, HC & Tan, P 2008, 'Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma', Journal of Hepatology, vol. 49, no. 1, pp. 52-60. https://doi.org/10.1016/j.jhep.2008.02.022

TY - JOUR

T1 - Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

AU - Huynh, H.

AU - Chow, P.K.H.

AU - Palanisamy, N.

AU - Salto-Tellez, Manuel

AU - Goh, B.C.

AU - Lee, C.K.

AU - Somani, A.

AU - Lee, H.S.

AU - Kalpana, R.

AU - Yu, K.

AU - Tan, P.H.

AU - Wu, J.

AU - Soong, R.

AU - Lee, M.H.

AU - Hor, H.

AU - Soo, K.C.

AU - Toh, H.C.

AU - Tan, P.

PY - 2008/7

Y1 - 2008/7

N2 - Background/Aims: Hepatocellular carcinoma is a leading cause of global cancer mortality, with standard chemotherapy being minimally effective in prolonging survival. We investigated if combined targeting of vascular endothelial growth factor protein and expression might affect hepatocellular carcinoma growth and angiogenesis.

AB - Background/Aims: Hepatocellular carcinoma is a leading cause of global cancer mortality, with standard chemotherapy being minimally effective in prolonging survival. We investigated if combined targeting of vascular endothelial growth factor protein and expression might affect hepatocellular carcinoma growth and angiogenesis.

U2 - 10.1016/j.jhep.2008.02.022

DO - 10.1016/j.jhep.2008.02.022

M3 - Article

VL - 49

SP - 52

EP - 60

JO - Journal of Hepatology

JF - Journal of Hepatology

SN - 0168-8278

IS - 1

ER -

Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma

Abstract

ASJC Scopus subject areas

UN SDGs

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