Bioactive Gyroid Scaffolds Formed by Sacrificial Templating of Nanocellulose and Nanochitin Hydrogels as Instructive Platforms for Biomimetic Tissue Engineering

Jose Guillermo Torres-Rendon; Tim Femmer; Laura De Laporte; Thomas Tigges; Khoshrow Rahimi; Felix Gremse; Sara Zafarnia; Wiltrud Lederle; Shinsuke Ifuku; Matthias Wessling; John G. Hardy; Andreas Walther

doi:10.1002/adma.201405873

Bioactive Gyroid Scaffolds Formed by Sacrificial Templating of Nanocellulose and Nanochitin Hydrogels as Instructive Platforms for Biomimetic Tissue Engineering

Jose Guillermo Torres-Rendon, Tim Femmer, Laura De Laporte, Thomas Tigges, Khoshrow Rahimi, Felix Gremse, Sara Zafarnia, Wiltrud Lederle, Shinsuke Ifuku, Matthias Wessling, John G. Hardy, Andreas Walther

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

195 Citations (Scopus)

2186 Downloads (Pure)

Abstract

A sacrificial templating process using lithographically printed minimal surface structures allows complex de novo geometries of delicate hydrogel materials. The hydrogel scaffolds based on cellulose and chitin nanofibrils show differences in terms of attachment of human mesenchymal stem cells, and allow their differentiation into osteogenic outcomes. The approach here serves as a first example toward designer hydrogel scaffolds viable for biomimetic tissue engineering.

Original language	English
Pages (from-to)	2989-2995
Number of pages	7
Journal	Advanced Materials
Volume	27
Issue number	19
Early online date	02 Apr 2015
DOIs	https://doi.org/10.1002/adma.201405873
Publication status	Published - 2015

Keywords

stem cells
cellulose nanofibrils
chitin nanofibrils
3D printing
hydrogel scaffolds

ASJC Scopus subject areas

Chemistry (miscellaneous)
General Materials Science
Biomaterials
Polymers and Plastics

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10.1002/adma.201405873

Bioactive Gyroid Scaffolds Formed by Sacrificial Templating of Nanocellulose and Nanochitin Hydrogels as Instructive Platforms for Biomimetic Tissue Engineering
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim This is the accepted version of article which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1002/adma.201405873/abstract;jsessionid=E5384D32009FB62F17FDD2F91ED91873.f04t01
Accepted author manuscript, 579 KB
Bioactive Gyroid Scaffolds Formed by Sacrificial Templating of Nanocellulose and Nanochitin Hydrogels as Instructive Platforms for Biomimetic Tissue Engineering -Supporting Information
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim This is the supporting information for the article which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1002/adma.201405873/abstract;jsessionid=E5384D32009FB62F17FDD2F91ED91873.f04t01
Accepted author manuscript, 3.27 MB

Cite this

Torres-Rendon, J. G., Femmer, T., De Laporte, L., Tigges, T., Rahimi, K., Gremse, F., Zafarnia, S., Lederle, W., Ifuku, S., Wessling, M., Hardy, J. G., & Walther, A. (2015). Bioactive Gyroid Scaffolds Formed by Sacrificial Templating of Nanocellulose and Nanochitin Hydrogels as Instructive Platforms for Biomimetic Tissue Engineering. Advanced Materials, 27(19), 2989-2995. https://doi.org/10.1002/adma.201405873

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abstract = "A sacrificial templating process using lithographically printed minimal surface structures allows complex de novo geometries of delicate hydrogel materials. The hydrogel scaffolds based on cellulose and chitin nanofibrils show differences in terms of attachment of human mesenchymal stem cells, and allow their differentiation into osteogenic outcomes. The approach here serves as a first example toward designer hydrogel scaffolds viable for biomimetic tissue engineering. ",

keywords = " stem cells, cellulose nanofibrils, chitin nanofibrils, 3D printing, hydrogel scaffolds",

author = "Torres-Rendon, {Jose Guillermo} and Tim Femmer and {De Laporte}, Laura and Thomas Tigges and Khoshrow Rahimi and Felix Gremse and Sara Zafarnia and Wiltrud Lederle and Shinsuke Ifuku and Matthias Wessling and Hardy, {John G.} and Andreas Walther",

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Torres-Rendon, JG, Femmer, T, De Laporte, L, Tigges, T, Rahimi, K, Gremse, F, Zafarnia, S, Lederle, W, Ifuku, S, Wessling, M, Hardy, JG & Walther, A 2015, 'Bioactive Gyroid Scaffolds Formed by Sacrificial Templating of Nanocellulose and Nanochitin Hydrogels as Instructive Platforms for Biomimetic Tissue Engineering', Advanced Materials, vol. 27, no. 19, pp. 2989-2995. https://doi.org/10.1002/adma.201405873

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T1 - Bioactive Gyroid Scaffolds Formed by Sacrificial Templating of Nanocellulose and Nanochitin Hydrogels as Instructive Platforms for Biomimetic Tissue Engineering

AU - Torres-Rendon, Jose Guillermo

AU - Femmer, Tim

AU - De Laporte, Laura

AU - Tigges, Thomas

AU - Rahimi, Khoshrow

AU - Gremse, Felix

AU - Zafarnia, Sara

AU - Lederle, Wiltrud

AU - Ifuku, Shinsuke

AU - Wessling, Matthias

AU - Hardy, John G.

AU - Walther, Andreas

PY - 2015

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AB - A sacrificial templating process using lithographically printed minimal surface structures allows complex de novo geometries of delicate hydrogel materials. The hydrogel scaffolds based on cellulose and chitin nanofibrils show differences in terms of attachment of human mesenchymal stem cells, and allow their differentiation into osteogenic outcomes. The approach here serves as a first example toward designer hydrogel scaffolds viable for biomimetic tissue engineering.

KW - stem cells

KW - cellulose nanofibrils

KW - chitin nanofibrils

KW - 3D printing

KW - hydrogel scaffolds

U2 - 10.1002/adma.201405873

DO - 10.1002/adma.201405873

M3 - Article

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EP - 2995

JO - Advanced Materials

JF - Advanced Materials

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ER -

Bioactive Gyroid Scaffolds Formed by Sacrificial Templating of Nanocellulose and Nanochitin Hydrogels as Instructive Platforms for Biomimetic Tissue Engineering

Abstract

Keywords

ASJC Scopus subject areas

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