Brønsted Acid Catalyzed Peterson Olefinations

Thomas K. Britten; Mark G. McLaughlin

doi:10.1021/acs.joc.9b02489

Brønsted Acid Catalyzed Peterson Olefinations

Thomas K. Britten, Mark G. McLaughlin

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

A mild and facile Peterson olefination has been developed employing low catalyst loading of the Brønsted acid HNTf2. The reactions are typically performed at room temperature, with the reaction tolerant to a range of useful functionalities. Furthermore, we have extended this methodology to the synthesis of enynes.

Original language	Undefined/Unknown
Pages (from-to)	301-305
Number of pages	5
Journal	The Journal of Organic Chemistry
Volume	85
Issue number	2
Early online date	27 Nov 2019
DOIs	https://doi.org/10.1021/acs.joc.9b02489
Publication status	Published - 17 Jan 2020
Externally published	Yes

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Cite this

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abstract = "A mild and facile Peterson olefination has been developed employing low catalyst loading of the Br{\o}nsted acid HNTf2. The reactions are typically performed at room temperature, with the reaction tolerant to a range of useful functionalities. Furthermore, we have extended this methodology to the synthesis of enynes.",

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AU - McLaughlin, Mark G.

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AB - A mild and facile Peterson olefination has been developed employing low catalyst loading of the Brønsted acid HNTf2. The reactions are typically performed at room temperature, with the reaction tolerant to a range of useful functionalities. Furthermore, we have extended this methodology to the synthesis of enynes.

U2 - 10.1021/acs.joc.9b02489

DO - 10.1021/acs.joc.9b02489

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SP - 301

EP - 305

JO - The Journal of Organic Chemistry

JF - The Journal of Organic Chemistry

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