Bridging the gap: Challenging lung infections and clinical trial development in cystic fibrosis

Damian G. Downey; Nicholas J. Simmonds; Silke van Koningsbruggen-Rietschel; Jutta Bend; Fiona Dunlevy; Kate Hill; Lieven  Dupont

doi:10.1016/j.jcf.2024.11.001

Bridging the gap: Challenging lung infections and clinical trial development in cystic fibrosis

Damian G. Downey, Nicholas J. Simmonds, Silke van Koningsbruggen-Rietschel, Jutta Bend, Fiona Dunlevy, Kate Hill, Lieven Dupont

Research output: Contribution to journal › Article › peer-review

Abstract

Despite the advances with cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy, many people living with cystic fibrosis continue to experience lung infections that are challenging to treat.
New treatment options and clinical trial strategies are essential to fill this urgent unmet medical need.

Original language	English
Journal	Journal of Cystic Fibrosis
Early online date	23 Nov 2024
DOIs	https://doi.org/10.1016/j.jcf.2024.11.001
Publication status	Early online date - 23 Nov 2024

Keywords

lung infections
cystic fibrosis
improved quality of life

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Pulmonary and Respiratory Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jcf.2024.11.001Licence: CC BY

Cite this

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title = "Bridging the gap: Challenging lung infections and clinical trial development in cystic fibrosis",

abstract = "Despite the advances with cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy, many people living with cystic fibrosis continue to experience lung infections that are challenging to treat.New treatment options and clinical trial strategies are essential to fill this urgent unmet medical need. ",

keywords = "lung infections, cystic fibrosis, improved quality of life",

author = "Downey, {Damian G.} and Simmonds, {Nicholas J.} and {van Koningsbruggen-Rietschel}, Silke and Jutta Bend and Fiona Dunlevy and Kate Hill and Lieven Dupont",

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AU - Downey, Damian G.

AU - Simmonds, Nicholas J.

AU - van Koningsbruggen-Rietschel, Silke

AU - Bend, Jutta

AU - Dunlevy, Fiona

AU - Hill, Kate

AU - Dupont, Lieven

PY - 2024/11/23

Y1 - 2024/11/23

N2 - Despite the advances with cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy, many people living with cystic fibrosis continue to experience lung infections that are challenging to treat.New treatment options and clinical trial strategies are essential to fill this urgent unmet medical need.

AB - Despite the advances with cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy, many people living with cystic fibrosis continue to experience lung infections that are challenging to treat.New treatment options and clinical trial strategies are essential to fill this urgent unmet medical need.

KW - lung infections

KW - cystic fibrosis

KW - improved quality of life

U2 - 10.1016/j.jcf.2024.11.001

DO - 10.1016/j.jcf.2024.11.001

M3 - Article

AN - SCOPUS:85210083525

SN - 1569-1993

JO - Journal of Cystic Fibrosis

JF - Journal of Cystic Fibrosis

ER -

Bridging the gap: Challenging lung infections and clinical trial development in cystic fibrosis

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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