Bridging the gap: challenging lung infections and clinical trial development in cystic fibrosis

Damian G. Downey; Nicholas J. Simmonds; Silke van Koningsbruggen-Rietschel; Jutta Bend; Fiona Dunlevy; Kate Hill; Lieven  Dupont

doi:10.1016/j.jcf.2024.11.001

Bridging the gap: challenging lung infections and clinical trial development in cystic fibrosis

Damian G. Downey^*
, Nicholas J. Simmonds
, Silke van Koningsbruggen-Rietschel
, Jutta Bend
, Fiona Dunlevy
, Kate Hill
, Lieven Dupont

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

26 Downloads (Pure)

Abstract

Despite the advances with cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy, many people living with cystic fibrosis continue to experience lung infections that are challenging to treat.

New treatment options and clinical trial strategies are essential to fill this urgent unmet medical need.

Original language	English
Pages (from-to)	79-82
Number of pages	4
Journal	Journal of Cystic Fibrosis
Volume	24
Issue number	1
Early online date	23 Nov 2024
DOIs	https://doi.org/10.1016/j.jcf.2024.11.001
Publication status	Published - Jan 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 4 Quality Education

Keywords

lung infections
cystic fibrosis
improved quality of life

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Pulmonary and Respiratory Medicine

Access to Document

10.1016/j.jcf.2024.11.001Licence: CC BY

Bridging the gap: challenging lung infections and clinical trial development in cystic fibrosis
Copyright 2024 The Authors. This is an open access article published under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
Final published version, 1.22 MBLicence: CC BY

Cite this

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title = "Bridging the gap: challenging lung infections and clinical trial development in cystic fibrosis",

abstract = "Despite the advances with cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy, many people living with cystic fibrosis continue to experience lung infections that are challenging to treat. New treatment options and clinical trial strategies are essential to fill this urgent unmet medical need.",

keywords = "lung infections, cystic fibrosis, improved quality of life",

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AU - van Koningsbruggen-Rietschel, Silke

AU - Bend, Jutta

AU - Dunlevy, Fiona

AU - Hill, Kate

AU - Dupont, Lieven

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AB - Despite the advances with cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapy, many people living with cystic fibrosis continue to experience lung infections that are challenging to treat. New treatment options and clinical trial strategies are essential to fill this urgent unmet medical need.

KW - lung infections

KW - cystic fibrosis

KW - improved quality of life

U2 - 10.1016/j.jcf.2024.11.001

DO - 10.1016/j.jcf.2024.11.001

M3 - Article

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Bridging the gap: challenging lung infections and clinical trial development in cystic fibrosis

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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Cite this