Can ultra-wide field retinal imaging replace colour digital stereoscopy for glaucoma detection?

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)
44 Downloads (Pure)

Abstract

Purpose
Ultra-wide field (UWF) retinal imaging (Optomap, Optos plc, Dunfermline, UK) is a novel technique to image the peripheral fundus. The goal of this study was to explore the potential use of UWF imaging to detect glaucoma, and specifically to evaluate the reproducibility of measures of vertical cup-to-disc ratio (VCDR) using ultra-wide field (UWF), and the agreement between UWF and standard colour digital stereoscopy (CDS).

Methods
An observational study. From a population-based epidemiological study we selected 100 eyes from 100 consecutive participants who were imaged using both standard CDS and UWF retinal imaging. Estimation of the VCDR using both modalities was made by a masked glaucoma specialist and two masked independent observers. Reliability and agreement between colour digital stereoscopy and the UWF imaging was assessed by Bland-Altman scatterplots.

Results
Intra-observer reproducibility of the UWF imaging in estimating VCDRs produced Limits of Agreement (LOA) ranging from −0.13 to 0.1 (mean 0.02) and −0.14 to 0.14 (mean 0.0004) for observer 1 and 2 respectively. Inter-observer reliability between observer 1 and the glaucoma specialist for VCDR measurements using CDS and UWF produced LOA ranging from −0.37 to 0.15 (mean −0.11) and −0.24 to 0.26 (mean 0.0005) respectively. Bland Altman plots produced LOA of −0.16 to 0.20 (mean 0.02) between the two imaging methods for assessing VCDR when carried out by a glaucoma specialist.

Conclusion
Grading of UWF imaging has high reproducibility in evaluating VCDR and agreement with stereoscopic optic disc imaging and may be suitable for glaucoma diagnosis in situations where CDS is not available.
Original languageEnglish
Pages (from-to)1-7
JournalOphthalmic Epidemiology
Early online date18 Sep 2017
DOIs
Publication statusEarly online date - 18 Sep 2017

Fingerprint

Dive into the research topics of 'Can ultra-wide field retinal imaging replace colour digital stereoscopy for glaucoma detection?'. Together they form a unique fingerprint.

Cite this