Abstract
Background: Metabolism by peptidases plays an important role in modulating the levels of biologically-active neuropeptides. The metabolism of the anti-inflammatory neuropeptide calcitonin gene-related peptide (GCRP), but not the pro-inflammatory neuropeptides substance P (SP) and neurokinin A (NKA) by components of the gingival crevicular fluid (GCF), could potentiate the inflammatory process in periodontitis.
| Original language | English |
|---|---|
| Pages (from-to) | 499-505 |
| Number of pages | 7 |
| Journal | Journal of Clinical Periodontology |
| Volume | 27 |
| Publication status | Published - 2000 |
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Dive into the research topics of 'Carboxypeptidase-mediated metabolism of calcitonin gene-related peptide in human gingival crevicular fluid - a role in periodontal inflammation?'. Together they form a unique fingerprint.Prizes
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Sir Wilfred Fish Research Prize. The British Society of Periodontology's most prestigious research prize
Lundy, F. (Recipient), 1999
Prize: Prize (including medals and awards)