Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini

Porntip Pinlaor; Natthawut Kaewpitoon; Thewarach Laha; Banchob Sripa; Sasithorn Kaewkes; Maria E Morales; Victoria H Mann; Sandi K Parriott; Sutas Suttiprapa; Mark W Robinson; Joyce To; John P Dalton; Alex Loukas; Paul J Brindley

doi:10.1371/journal.pntd.0000398

Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini

Porntip Pinlaor, Natthawut Kaewpitoon, Thewarach Laha, Banchob Sripa, Sasithorn Kaewkes, Maria E Morales, Victoria H Mann, Sandi K Parriott, Sutas Suttiprapa, Mark W Robinson, Joyce To, John P Dalton, Alex Loukas, Paul J Brindley

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

63 Citations (Scopus)

Abstract

The liver fluke Opisthorchis viverrini is classified as a class I carcinogen due to the association between cholangiocarcinoma and chronic O. viverrini infection. During its feeding activity within the bile duct, the parasite secretes several cathepsin F cysteine proteases that may induce or contribute to the pathologies associated with hepatobiliary abnormalities.

Original language	English
Article number	e398
Pages (from-to)	e398
Journal	PLoS Neglected Tropical Diseases
Volume	3
Issue number	3
DOIs	https://doi.org/10.1371/journal.pntd.0000398
Publication status	Published - 2009

ASJC Scopus subject areas

Infectious Diseases
Public Health, Environmental and Occupational Health
Pharmacology, Toxicology and Pharmaceutics(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1371/journal.pntd.0000398

Cite this

Pinlaor, P., Kaewpitoon, N., Laha, T., Sripa, B., Kaewkes, S., Morales, M. E., Mann, V. H., Parriott, S. K., Suttiprapa, S., Robinson, M. W., To, J., Dalton, J. P., Loukas, A., & Brindley, P. J. (2009). Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini. PLoS Neglected Tropical Diseases, 3(3), e398. Article e398. https://doi.org/10.1371/journal.pntd.0000398

@article{9d3532173298401085943d92c7167e32,

title = "Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini",

abstract = "The liver fluke Opisthorchis viverrini is classified as a class I carcinogen due to the association between cholangiocarcinoma and chronic O. viverrini infection. During its feeding activity within the bile duct, the parasite secretes several cathepsin F cysteine proteases that may induce or contribute to the pathologies associated with hepatobiliary abnormalities.",

author = "Porntip Pinlaor and Natthawut Kaewpitoon and Thewarach Laha and Banchob Sripa and Sasithorn Kaewkes and Morales, {Maria E} and Mann, {Victoria H} and Parriott, {Sandi K} and Sutas Suttiprapa and Robinson, {Mark W} and Joyce To and Dalton, {John P} and Alex Loukas and Brindley, {Paul J}",

year = "2009",

doi = "10.1371/journal.pntd.0000398",

language = "English",

volume = "3",

pages = "e398",

journal = "PLoS Neglected Tropical Diseases",

publisher = "Public Library of Science",

number = "3",

}

TY - JOUR

T1 - Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini

AU - Pinlaor, Porntip

AU - Kaewpitoon, Natthawut

AU - Laha, Thewarach

AU - Sripa, Banchob

AU - Kaewkes, Sasithorn

AU - Morales, Maria E

AU - Mann, Victoria H

AU - Parriott, Sandi K

AU - Suttiprapa, Sutas

AU - Robinson, Mark W

AU - To, Joyce

AU - Dalton, John P

AU - Loukas, Alex

AU - Brindley, Paul J

PY - 2009

Y1 - 2009

N2 - The liver fluke Opisthorchis viverrini is classified as a class I carcinogen due to the association between cholangiocarcinoma and chronic O. viverrini infection. During its feeding activity within the bile duct, the parasite secretes several cathepsin F cysteine proteases that may induce or contribute to the pathologies associated with hepatobiliary abnormalities.

AB - The liver fluke Opisthorchis viverrini is classified as a class I carcinogen due to the association between cholangiocarcinoma and chronic O. viverrini infection. During its feeding activity within the bile duct, the parasite secretes several cathepsin F cysteine proteases that may induce or contribute to the pathologies associated with hepatobiliary abnormalities.

U2 - 10.1371/journal.pntd.0000398

DO - 10.1371/journal.pntd.0000398

M3 - Article

C2 - 19308250

VL - 3

SP - e398

JO - PLoS Neglected Tropical Diseases

JF - PLoS Neglected Tropical Diseases

IS - 3

M1 - e398

ER -

Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

Fingerprint

Cite this