Change is in the air: key questions on the 'Treatable Traits' model for chronic airway diseases in primary care

Alvar Agusti, Peter G Gibson, Liam G Heaney, Mike Thomas

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)
6 Downloads (Pure)

Abstract

Despite great advancements in the treatment of chronic airway diseases, improvements in morbidity and mortality have stalled in recent years. Asthma and chronic obstructive pulmonary disease are complex and heterogeneous diseases that require tailored management based on individual patient characteristics and needs. The Treatable Traits (TTs) approach aims to personalise and improve patient care through the identification and targeting of clinically relevant and modifiable pulmonary, extra-pulmonary and behavioural traits. In this article, we outline the rationale for TTs-based management and provide practical guidance for its application in primary care. To aid implementation, seven potential 'prime' traits are proposed: airflow obstruction, eosinophilic inflammation, adherence, inhaler technique, smoking, low body mass index/obesity and anxiety and depression-selected for their prevalence, recognisability and feasibility of use. Some of the key questions among healthcare professionals, that may be roadblocks to widespread application of a TTs model of care, are also addressed.
Original languageEnglish
Article number21
Journalnpj Primary Care Respiratory Medicine
Volume34
Early online date18 Jul 2024
DOIs
Publication statusEarly online date - 18 Jul 2024

Keywords

  • Humans
  • Depression - therapy
  • Pulmonary Disease, Chronic Obstructive - therapy - physiopathology
  • Primary Health Care
  • Smoking - epidemiology - adverse effects
  • Asthma - therapy
  • Obesity - therapy
  • Anxiety

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