Characterization and modelling the mechanical behaviour of poly(l-lactic acid) for the manufacture of bioresorbable vascular scaffolds by stretch blow moulding

Huidong Wei, Shiyong Yan, Gary Menary, Saurav Goel

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Abstract

Bioresorbable Vascular Scaffolds (BVS) manufactured from poly (l-lactic acid) (PLLA) offer an alternative to metal scaffolds for the treatment of coronary heart disease. One of the key steps in the manufacture of these scaffolds is the stretch blow moulding process where the PLLA is biaxially stretched above glass transition temperature (Tg), inducing biaxial orientation and thus increasing ductility, strength and stiffness. To optimise the manufacture and performance of these scaffolds it is important to understand the influence of temperature and strain rate on the constitutive behaviour of PLLA in the blow moulding process. Experiments have been performed on samples of PLLA on a custom built biaxial stretch testing machine to replicate conditions typically experienced during blow moulding i.e. in a temperature range from 70 °C to 100 °C and at strain rates of 1 s−1, 4 s−1 and 16 s−1 respectively. The data is subsequently used to calibrate a nonlinear viscoelastic material model to represent the deformation behaviour of PLLA in the blow moulding process. The results highlight the significance of temperature and strain rate on the yielding and strain hardening behaviour of PLLA and the ability of the selected model to capture it.
Original languageEnglish
Pages (from-to)43-57
Number of pages14
JournalInternational Journal of Material Forming
Volume13
Issue number1
DOIs
Publication statusPublished - 10 Jan 2020

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Lactic acid
Blow molding
Scaffolds
Lactic Acid
Strain rate
Strain hardening
Temperature
Ductility
Metals
Stiffness
Testing
Experiments

Keywords

  • Mechanical behaviour Constitutive model PLLA Glass transition Stretch blow moulding

Cite this

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abstract = "Bioresorbable Vascular Scaffolds (BVS) manufactured from poly (l-lactic acid) (PLLA) offer an alternative to metal scaffolds for the treatment of coronary heart disease. One of the key steps in the manufacture of these scaffolds is the stretch blow moulding process where the PLLA is biaxially stretched above glass transition temperature (Tg), inducing biaxial orientation and thus increasing ductility, strength and stiffness. To optimise the manufacture and performance of these scaffolds it is important to understand the influence of temperature and strain rate on the constitutive behaviour of PLLA in the blow moulding process. Experiments have been performed on samples of PLLA on a custom built biaxial stretch testing machine to replicate conditions typically experienced during blow moulding i.e. in a temperature range from 70 °C to 100 °C and at strain rates of 1 s−1, 4 s−1 and 16 s−1 respectively. The data is subsequently used to calibrate a nonlinear viscoelastic material model to represent the deformation behaviour of PLLA in the blow moulding process. The results highlight the significance of temperature and strain rate on the yielding and strain hardening behaviour of PLLA and the ability of the selected model to capture it.",
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N2 - Bioresorbable Vascular Scaffolds (BVS) manufactured from poly (l-lactic acid) (PLLA) offer an alternative to metal scaffolds for the treatment of coronary heart disease. One of the key steps in the manufacture of these scaffolds is the stretch blow moulding process where the PLLA is biaxially stretched above glass transition temperature (Tg), inducing biaxial orientation and thus increasing ductility, strength and stiffness. To optimise the manufacture and performance of these scaffolds it is important to understand the influence of temperature and strain rate on the constitutive behaviour of PLLA in the blow moulding process. Experiments have been performed on samples of PLLA on a custom built biaxial stretch testing machine to replicate conditions typically experienced during blow moulding i.e. in a temperature range from 70 °C to 100 °C and at strain rates of 1 s−1, 4 s−1 and 16 s−1 respectively. The data is subsequently used to calibrate a nonlinear viscoelastic material model to represent the deformation behaviour of PLLA in the blow moulding process. The results highlight the significance of temperature and strain rate on the yielding and strain hardening behaviour of PLLA and the ability of the selected model to capture it.

AB - Bioresorbable Vascular Scaffolds (BVS) manufactured from poly (l-lactic acid) (PLLA) offer an alternative to metal scaffolds for the treatment of coronary heart disease. One of the key steps in the manufacture of these scaffolds is the stretch blow moulding process where the PLLA is biaxially stretched above glass transition temperature (Tg), inducing biaxial orientation and thus increasing ductility, strength and stiffness. To optimise the manufacture and performance of these scaffolds it is important to understand the influence of temperature and strain rate on the constitutive behaviour of PLLA in the blow moulding process. Experiments have been performed on samples of PLLA on a custom built biaxial stretch testing machine to replicate conditions typically experienced during blow moulding i.e. in a temperature range from 70 °C to 100 °C and at strain rates of 1 s−1, 4 s−1 and 16 s−1 respectively. The data is subsequently used to calibrate a nonlinear viscoelastic material model to represent the deformation behaviour of PLLA in the blow moulding process. The results highlight the significance of temperature and strain rate on the yielding and strain hardening behaviour of PLLA and the ability of the selected model to capture it.

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