Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MSn and Their Mutagenic Activity

FABIANA V. ZANUTTO, Paula Karina Boldrin, Samara Fernandes de Souza, Eliana Aparecida Varanda, Paulo Takeo Sano, Wagner Vilegas, Lourdes Campaner dos Santos

Research output: Working paper

Abstract

A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a.
Original languageEnglish
Place of PublicationMolecules
Pages244-262
Number of pages18
Volume18
Publication statusPublished - 27 Dec 2012

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