Characterization of flavonoids and naphthopyranones in methanol extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MSn and their mutagenic activity

Fabiana Volpe  Zanutto; Paula Karina Boldrin; Eliana Aparecida  Varanda; Samara Fernandes de Souza; Paulo Takeo Sano; Wagner Vilegas; Lourdes Campaner dos Santos

doi:10.3390/molecules18010244

Characterization of flavonoids and naphthopyranones in methanol extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MSⁿ and their mutagenic activity

Fabiana Volpe Zanutto
, Paula Karina Boldrin
, Eliana Aparecida Varanda
, Samara Fernandes de Souza
, Paulo Takeo Sano
, Wagner Vilegas
, Lourdes Campaner dos Santos^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

6 Downloads (Pure)

Abstract

A HPLC-ESI-IT-MSⁿ method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a.

Original language	English
Pages (from-to)	244-262
Number of pages	19
Journal	Molecules
Volume	18
Issue number	1
Early online date	27 Dec 2012
DOIs	https://doi.org/10.3390/molecules18010244
Publication status	Published - Jan 2013
Externally published	Yes

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10.3390/molecules18010244Licence: CC BY

Characterization of flavonoids and naphthopyranones in methanol extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MSn and their mutagenic activity
Copyright 2013 The Authors. This is an open access article published under a Creative Commons Attribution License (https://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
Final published version, 427 KBLicence: CC BY

Cite this

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abstract = "A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a. ",

author = "Zanutto, \{Fabiana Volpe\} and Boldrin, \{Paula Karina\} and Varanda, \{Eliana Aparecida\} and \{Fernandes de Souza\}, Samara and \{Takeo Sano\}, Paulo and Wagner Vilegas and \{Campaner dos Santos\}, Lourdes",

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AU - Zanutto, Fabiana Volpe

AU - Boldrin, Paula Karina

AU - Varanda, Eliana Aparecida

AU - Fernandes de Souza, Samara

AU - Takeo Sano, Paulo

AU - Vilegas, Wagner

AU - Campaner dos Santos, Lourdes

PY - 2013/1

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N2 - A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a.

AB - A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a.

U2 - 10.3390/molecules18010244

DO - 10.3390/molecules18010244

M3 - Article

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JF - Molecules

IS - 1

ER -

Characterization of flavonoids and naphthopyranones in methanol extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MSn and their mutagenic activity

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Characterization of flavonoids and naphthopyranones in methanol extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MSⁿ and their mutagenic activity