CHD4 loss alters chromatin accessibility giving rise to sensitivity to DNA damage repair compounds in acute myeloid leukaemia

Deirdra Venney; Graeme M. Greenfield; Lauren V. Cairns; Paul Strain; Áine E. McGill; Jonathan J. Morgan; Róisín M. McAvera; Fatemeh Mirzadeh; Yaser Atlasi; Adone Mohd-Sarip; Ken I. Mills

doi:10.1182/blood-2022-162764

CHD4 loss alters chromatin accessibility giving rise to sensitivity to DNA damage repair compounds in acute myeloid leukaemia

Deirdra Venney^*, Graeme M. Greenfield, Lauren V. Cairns, Paul Strain, Áine E. McGill, Jonathan J. Morgan, Róisín M. McAvera, Fatemeh Mirzadeh, Yaser Atlasi, Adone Mohd-Sarip, Ken I. Mills

^*Corresponding author for this work

School of Medicine, Dentistry and Biomedical Sciences

Research output: Contribution to journal › Meeting abstract › peer-review

Original language	English
Pages (from-to)	8702-8703
Journal	Blood
Volume	140
Issue number	Supplement 1
DOIs	https://doi.org/10.1182/blood-2022-162764
Publication status	Published - 15 Nov 2022
Event	64th American Society of Hematology Annual Meeting - New Orleans, United States Duration: 10 Dec 2022 → 13 Dec 2022

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10.1182/blood-2022-162764Licence: Unspecified

Elucidating the role of CHD4 as a chromatin and epigenetic modifier in acute myeloid leukaemia
Author: Venney, D., Jul 2023
Supervisor: Mills, K. (Supervisor), Tielenius Kruythoff-Mohd Sarip, A. (Supervisor) & Atlasi, Y. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy

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Venney, D., Greenfield, G. M., Cairns, L. V., Strain, P., McGill, Á. E., Morgan, J. J., McAvera, R. M., Mirzadeh, F., Atlasi, Y., Mohd-Sarip, A., & Mills, K. I. (2022). CHD4 loss alters chromatin accessibility giving rise to sensitivity to DNA damage repair compounds in acute myeloid leukaemia. Blood, 140(Supplement 1), 8702-8703. https://doi.org/10.1182/blood-2022-162764

@article{64e4d9cede144eb9935659f7715aff15,

title = "CHD4 loss alters chromatin accessibility giving rise to sensitivity to DNA damage repair compounds in acute myeloid leukaemia",

author = "Deirdra Venney and Greenfield, {Graeme M.} and Cairns, {Lauren V.} and Paul Strain and McGill, {{\'A}ine E.} and Morgan, {Jonathan J.} and McAvera, {R{\'o}is{\'i}n M.} and Fatemeh Mirzadeh and Yaser Atlasi and Adone Mohd-Sarip and Mills, {Ken I.}",

year = "2022",

month = nov,

day = "15",

doi = "10.1182/blood-2022-162764",

language = "English",

volume = "140",

pages = "8702--8703",

journal = "Blood",

issn = "0006-4971",

publisher = "AMER SOC HEMATOLOGY",

number = "Supplement 1",

note = "64th American Society of Hematology Annual Meeting ; Conference date: 10-12-2022 Through 13-12-2022",

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TY - JOUR

T1 - CHD4 loss alters chromatin accessibility giving rise to sensitivity to DNA damage repair compounds in acute myeloid leukaemia

AU - Venney, Deirdra

AU - Greenfield, Graeme M.

AU - Cairns, Lauren V.

AU - Strain, Paul

AU - McGill, Áine E.

AU - Morgan, Jonathan J.

AU - McAvera, Róisín M.

AU - Mirzadeh, Fatemeh

AU - Atlasi, Yaser

AU - Mohd-Sarip, Adone

AU - Mills, Ken I.

PY - 2022/11/15

Y1 - 2022/11/15

U2 - 10.1182/blood-2022-162764

DO - 10.1182/blood-2022-162764

M3 - Meeting abstract

VL - 140

SP - 8702

EP - 8703

JO - Blood

JF - Blood

SN - 0006-4971

IS - Supplement 1

T2 - 64th American Society of Hematology Annual Meeting

Y2 - 10 December 2022 through 13 December 2022

ER -

CHD4 loss alters chromatin accessibility giving rise to sensitivity to DNA damage repair compounds in acute myeloid leukaemia

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Student theses

Elucidating the role of CHD4 as a chromatin and epigenetic modifier in acute myeloid leukaemia

Cite this