Chemical properties and protective effect of Rosmarinus officinalis: Mitigation of lipid peroxidation and DNA-damage from arsenic exposure

G. J. Farias*, D. V. Frescura, A. A. Boligon, C. K. Trapp, L. J. Andriolo, B. S. Tedesco, K. Bernardy, R. Schwalbert, K. B. Del Frari, M. Carey, T. F. Nicoloso

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)
7 Downloads (Pure)

Abstract

Recent studies have implicated dietary factors in the cause and prevention of important diseases, with strong evidence that plant's compounds can protect against these diseases. Moreover, food security and environmental contamination are topics in focus at the moment. In this view, contamination by arsenic (As) has received much attention as well as some spices with medicinal properties. Among these plants, the use of Rosmarinus officinalis L. has demonstrated antioxidant properties besides being used for circulatory disorders. Therefore, we measured the mitotic index of Allium cepa L. and characterized the antioxidant effects to determine the capacity of R. officinalis to ameliorate arsenic-induced DNA damages. R. officinalis extract showed no mutagenic effects and exhibited antimutagenic potential, reducing the DNA damages, anaphase-telophase bridges and micronuclei chromosome aberrations that result from treatment with the arsenic. Additionally, reduction in arsenic-induced lipid peroxidation was also observed.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalJournal of Applied Botany and Food Quality
Volume91
DOIs
Publication statusPublished - 28 Feb 2018

Keywords

  • Arsenate
  • Cytogenetic
  • Heavy metal
  • Medicinal plant
  • Rosemary

ASJC Scopus subject areas

  • Food Science
  • Plant Science

Fingerprint

Dive into the research topics of 'Chemical properties and protective effect of Rosmarinus officinalis: Mitigation of lipid peroxidation and DNA-damage from arsenic exposure'. Together they form a unique fingerprint.

Cite this