Chemoenzymatic synthesis of chiral 4,4 '-bipyridyls and their metal-organic frameworks

Lenuta Sbircea, Narain Sharma, W. Clegg, R.W. Harrington, Patricia Horton, M.B. Hursthouse, D.C. Apperley, Derek Boyd, Stuart James

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)

Abstract

The first enantiopure 4,4'-bipyridyls, 6, 8, and 9 have been prepared in four or five steps via bacterial dioxygenase-catalysed cis-dihydroxylation of 4-chloroquinoline 1 and C-C coupling; ligands 6 and 9 are found to be effective building blocks for the preparation of chiral metal-organic frameworks as demonstrated with the rational synthesis of two pillared-grid structures [Zn-2(fumarate)(2)(L)], which exhibit interesting structural and dynamic aspects.
Original languageEnglish
Pages (from-to)5538-5540
Number of pages3
JournalChemical Communications
Volume1
Issue number43
DOIs
Publication statusPublished - 2008

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Ceramics and Composites
  • Electronic, Optical and Magnetic Materials
  • Materials Chemistry
  • Metals and Alloys
  • Surfaces, Coatings and Films

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