Chemoenzymatic synthesis of enantiopure dihydroxy-1,2,3,4-tetrahydronaphthalenes from naphthalene and dihydronaphthalene precursors

Derek Boyd, Narain Sharma, N.A. Kerley, G. McConville, Christopher Allen, A.J. Blacker

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

cis-Dihydrodiol, cis-tetrahydrodiol and arene hydrate bacterial metabolites, of naphthalene and 1,2-dihydronaphthalene, have been used as synthetic precursors; chemoenzymatic and enzyme-catalysed syntheses have been used to obtain all possible enantiopure samples of dihydroxy-1,2,3,4-tetrahydronaphthalene stereoisomers.
Original languageEnglish
Pages (from-to)32-48
Number of pages17
JournalArkivoc
Volume5
Issue number7
Publication statusPublished - 2003

ASJC Scopus subject areas

  • Organic Chemistry

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