Chlorhexidine release from poly(epsilon-caprolactone) films prepared by solvent evaporation

N.J. Medlicott, I.G. Tucker, M.J. Rathbone, D.W. Holborow, David Jones

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

The effect of selected formulation variables on the release of chlorhexidine from poly(epsilon-caprolactone) films was evaluated in vitro using a complete factorial experimental design. Repeated measures analysis of variance showed chlorhexidine type (diacetate or base), drug load (10, 20 or 30% w/w), chlorhexidine particle size (
Original languageEnglish
Pages (from-to)25-35
Number of pages11
JournalInternational Journal of Pharmaceutics
Volume143
Publication statusPublished - 1996

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