The effect of selected formulation variables on the release of chlorhexidine from poly(epsilon-caprolactone) films was evaluated in vitro using a complete factorial experimental design. Repeated measures analysis of variance showed chlorhexidine type (diacetate or base), drug load (10, 20 or 30% w/w), chlorhexidine particle size (
|Number of pages||11|
|Journal||International Journal of Pharmaceutics|
|Publication status||Published - 1996|
Medlicott, N. J., Tucker, I. G., Rathbone, M. J., Holborow, D. W., & Jones, D. (1996). Chlorhexidine release from poly(epsilon-caprolactone) films prepared by solvent evaporation. International Journal of Pharmaceutics, 143, 25-35.