Choosing intraocular lenses in patients undergoing bilateral cataract extraction - one size does not fit all

Standard pairwise meta-analysis compares 2 interventions at a time, for example, treatment A vs treatment B. By contrast, network meta-analysis (NMA) compares 3 or more interventions in a single analysis by combining direct evidence within studies and indirect evidence based on a common comparator across a network of studies. In addition to estimates of the relative effects between any pair of interventions in the network, treatment ranking is a very informative output of NMA. However, inappropriate interpretation and overinterpretation of ranking statistics can misinform clinical decision-making.